TLS Online TPP Program

#Question id: 5807


Which of the following would be an example of a germline mutation?

#Unit 8. Inheritance Biology
  1. Exposure to excessive UV radiation causes changes in the DNA of a skin cell, leading to basal cell carcinoma (skin cancer).

  2. In a very early human embryo, a mistake in mitosis causes loss of a Y chromosome in one daughter cell. The resulting child is a fertile male who is chromosomally partially male (XY) and partially female with Turner's syndrome (XO).

  3. A man with normal chromosomes has a hip X-ray without a protective shield. Ten months later, his wife gives birth to a child with a chromosomal deletion.

  4. An embryo missing one copy of the third chromosome is miscarried very early in pregnancy.

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TLS Online TPP Program

#Question id: 4509

#Unit 3. Fundamental Processes

Which group of introns contain an “internal guide sequence”

TLS Online TPP Program

#Question id: 4510

#Unit 3. Fundamental Processes

Which statements are true about group I and group II introns,

A. Group I (and II) introns are not enzymes because they have a turnover number of only 1.

B. A third transesterification reaction can occur to cyclize the intron.

C. They cannot be readily converted into ribozymes.

D. It is similar to the way that the self-cleaving Hammerhead could be converted to a ribozyme by separating the active site from the substrate

TLS Online TPP Program

#Question id: 4511

#Unit 3. Fundamental Processes

The proteins are not needed for the splicing reaction itself, because

TLS Online TPP Program

#Question id: 4512

#Unit 3. Fundamental Processes

Some pre-mRNAs can be spliced in more than one way. Thus, mRNAs containing different selections of exons can be generated from a given pre-mRNA, called

TLS Online TPP Program

#Question id: 4513

#Unit 3. Fundamental Processes

Different snRNPs recognize the same (or overlapping) sequences in the pre-mRNA at different stages of the splicing reaction, which two snRNPs recognizing the 5’ splice site

TLS Online TPP Program

#Question id: 4514

#Unit 3. Fundamental Processes

What is true about coactivators,

A. The coactivators act directly by binding to the DNA

B. The coactivators act indirectly—not by binding to the DNA

C. Are required for essential communication between the activators and the complex composed of Pol II.

D. Are required for essential communication between the and the basal (or general) transcription factors.