TLS Online TPP Program

#Question id: 5807


Which of the following would be an example of a germline mutation?

#Unit 8. Inheritance Biology
  1. Exposure to excessive UV radiation causes changes in the DNA of a skin cell, leading to basal cell carcinoma (skin cancer).

  2. In a very early human embryo, a mistake in mitosis causes loss of a Y chromosome in one daughter cell. The resulting child is a fertile male who is chromosomally partially male (XY) and partially female with Turner's syndrome (XO).

  3. A man with normal chromosomes has a hip X-ray without a protective shield. Ten months later, his wife gives birth to a child with a chromosomal deletion.

  4. An embryo missing one copy of the third chromosome is miscarried very early in pregnancy.