#Question id: 7263
#Unit 5. Developmental Biology
Following statements are regarding to the drosophila.
A. At the completion of oogenesis, the bicoid message is
anchored at the anterior end of the oocyte and the nanos message is tethered to
the posterior end in translationally dormant condition.
B. The translation inhibitors Smaug and CUP. Smaug binds to
the 3’UTR of both bicoid and nanos mRNA and recruits the CUP protein that
prevents the association of the message with the ribosome as well as recruiting
other proteins that deadenylate the message and target it for degradation.
C. The bicoid-Exuperantia complex is transported out of the
nurse cells and into the oocyte via microtubules (Kinesin ATPase).
D. Two other maternally provided mRNAs—caudal and hunchback
are critical for patterning the anterior and posterior regions of the body
plan, respectively.
Which of the following combination is correct?