TLS Online TPP Program

#Question id: 6976


What is the major concern of using retroviral vectors to deliver or activate pluripotent genes?

#Unit 5. Developmental Biology
  1. Not very efficient and needs repeated transfections
  2. Plasmid diluted as iPS cells divide
  3. Vector and transgenes remain in the genome and can be reactivated in differentiated cells
  4. The vector integrates but is excised by the transposase

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TLS Online TPP Program

#Question id: 2436

#Unit 2. Cellular Organization

Cell locomotion

a. requires coordination of motions generated in different regions of the cell.

b. occurs only in cells with a defined polarity.

c. may be controlled by signaling pathways.

d. occurs in a defined sequence of steps.

TLS Online TPP Program

#Question id: 2437

#Unit 2. Cellular Organization

Membrane extension involves

a. bending actin filaments.                   

b. myosin II.

c. the Arp2/3 nucleation of new filaments.

d. actin depolymerization.     

e. actin polymerization.

TLS Online TPP Program

#Question id: 2438

#Unit 2. Cellular Organization

Rac, a GTPase superfamily protein,

a. is related to Ras.                             

b. may be activated by growth factors.

c. stimulates lamellipodia formation. 

d. stimulates filopodia formation.

e. stimulates stress fiber assembly.

TLS Online TPP Program

#Question id: 2439

#Unit 2. Cellular Organization

α- and β-tubulin

a. are highly conserved.                                 

b. bind GTP.

c. hydrolyze GTP to GDP.                 

d. are found in all eukaryotes.

e. are related to the bacterial protein FtsZ.

TLS Online TPP Program

#Question id: 2440

#Unit 2. Cellular Organization

Microtubule assembly in vitro requires

a. ATP.                                                           

b. a threshold (critical) concentration of tubulin.

c. warming the solution to 37°C.                   

d. microtubule-associated proteins.         

e. GTP.

TLS Online TPP Program

#Question id: 2441

#Unit 2. Cellular Organization

Which of the following statement(s) is (are) true of microtubule assembly?

a. GDP-tubulin normally assembles into microtubules.

b. Microtubule (-) ends grow faster than microtubule (+) ends.

c. Tubulin subunits assemble to form a protofilament.

d. Microtubules consist of multiple protofilaments.

e. Microtubules with a GTP cap will shorten.