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TLS Online TPP Program

#Question id: 30114

In the case of monoclonal antibody production by hybridoma technology, myeloma cells used lack the enzyme hypxanthine - guanine phosphoriboxyl transferase(HGPRT) such that fused cells can only survive when selected on hypoxanthine-aminopterinthymdine (HAT). What is the role of aminopterin in this medium?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. To be used as cell cycle inhibitor of myeloma cells.
  2. To block the pathway for nucleotide synthesis.
  3. To facilitate fusion of Myeloid B cells and antibody producing B cells.
  4. To facilitate production of antibody producing B cells.
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TLS Online TPP Program

#Question id: 8854

#Unit 9. Diversity of Life Forms

Which cells in a sponge are primarily responsible for trapping and removing food particles from circulating water?
TLS Online TPP Program

#Question id: 19695

#Unit 13. Methods in Biology

Which of the following leads are used to record ECG by using two active electrodes?
TLS Online TPP Program

#Question id: 4951

#Unit 11. Evolution and Behavior

The synthesis of new DNA requires the prior existence of oligonucleotides to serve as primers. On Earth, these primers are small RNA molecules. This latter observation is evidence in support of the hypothesized existence of
TLS Online TPP Program

#Question id: 2484

#Unit 2. Cellular Organization

The EB1 protein has several functions.  Which of the following is/are true regarding EB1?
TLS Online TPP Program

#Question id: 13018

#Unit 10. Ecological Principles

Generalized global air circulation and precipitation patterns are caused by