#Question id: 15417
#Unit 5. Developmental Biology
#Question id: 111
#Unit 1. Molecules and their Interaction Relevant to Biology
Sterols are steroids which have
#Question id: 15306
#Unit 4. Cell Communication and Cell Signaling
The transformation of a normal cell to a cancer cell is accompanied by the loss of function of one or more tumor‐suppressor genes. High‐throughput sequencing studies have identified hundreds of genes that are implicated as tumor suppressors in humans. Some of the better characterized genes;
|
Gene |
Primary tumor |
Proposed function |
|
i) APC |
Colorectal |
Binds β
‐catenin acting as transcription factor |
|
ii) BRCA1 |
Breast |
DNA repair |
|
iii) MSH2, MLH1 |
Melanoma, pancreatic |
p16: Cdk inhibitor ARF: stabilizes p53 |
|
iv) E‐Cadherin |
Breast, colon |
Cell adhesion molecule |
|
v) INK4a |
Colorectal |
Mismatch repair |
|
vi) NF1 |
Neurofibromas |
Activates GTPase of Ras |
Choose incorrect matching regarding tumor‐suppressor genes/primary tumor/proposed functions; |
#Question id: 3372
#Unit 11. Evolution and Behavior
Fish, penguin and Dolphin are independently evolved similar traits as a result of having to adapt to similar environments or ecological niches.
A. On a molecular level, this can happen due to random mutation in unrelated taxon to adaptive changes
B. This is the example of divergent evolution, occurred due to similar group of organisms inhabiting different environments
C. Similar phenotype are produced by identical change in orthologous gene
D. This is the example of convergent evolution, occurred due to similar group of organisms inhabiting different environments
Which of the following is the correct combination?
#Question id: 5750
#Unit 8. Inheritance Biology
type of microorganism that can exist on minimal medium