TLS Online TPP Program

#Question id: 31092


GPCR pathway mainly via a G protein called Gq, activates PLC-b. Mentioned below are some of the steps. Which of the following not correct?

#Unit 4. Cell Communication and Cell Signaling
  1. PLC-b acts on phosphatidyl inositol 4,5-biphosphate (PIP2), which is present in the inner half of the plasma membrane lipid bilayer.
  2. Activated PLC-p cleaves the PIP2 to generate two products: inositol 1,4,5- triphosphate (IP3) and diacylglycerol (DAG).
  3. IP3 is a small lipid-soluble molecule that binds to IP3 receptor on plasma membrane thereby increasing Ca2+ concentration in the cytosol.
  4. DAG gets further cleaved to release arachidonic acid, which is used in the synthesis of eicosanoids including prostaglandins. DAG also activates ca2+ dependent PKC.
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TLS Online TPP Program

#Question id: 5356

#Unit 8. Inheritance Biology

In the following pedigree, individuals with shaded circle or shaded square show presence of a recessive autosomal trait. The calculated risk of occurrence of this trait for III-I is

TLS Online TPP Program

#Question id: 5357

#Unit 8. Inheritance Biology

This pedigree shows the inheritance of a recessive trait in humans. Individuals that have the trait are homozygous for a recessive allele a. If H and I, who happen to be first cousins, marry and have a child, what is the chance that this child will have the recessive trait?

TLS Online TPP Program

#Question id: 5358

#Unit 8. Inheritance Biology

In the following pedigree, individuals with shaded show presence of a recessive autosomal trait. If all individual is coming from outside the family is homozygous for normal. The calculated risk of occurrence of this trait for (?) individual is 

TLS Online TPP Program

#Question id: 5359

#Unit 8. Inheritance Biology

Which of the following mode of inheritance and selected individuals must be carrier showing in above pedigree?

TLS Online TPP Program

#Question id: 5360

#Unit 1. Molecules and their Interaction Relevant to Biology

Following some different genetic disorder traces in families. 

Family

Father

Mother

Son

Daughter

A

Affected

Affected

Unaffected

Unaffected

B

Affected

Affected

Unaffected

Affected

C

Unaffected

Unaffected

Undetermined 

Affected

D

Affected

Unaffected

Unaffected

Affected

 Which of the following possible mode of inheritance in the Family A, B, C and D respectively

TLS Online TPP Program

#Question id: 5360

#Unit 8. Inheritance Biology

Following some different genetic disorder traces in families. 

Family

Father

Mother

Son

Daughter

A

Affected

Affected

Unaffected

Unaffected

B

Affected

Affected

Unaffected

Affected

C

Unaffected

Unaffected

Undetermined 

Affected

D

Affected

Unaffected

Unaffected

Affected

 Which of the following possible mode of inheritance in the Family A, B, C and D respectively