#Question id: 1481
#Unit 4. Cell Communication and Cell Signaling
XIAP, one member of a family of inhibitor of apoptosis proteins (IAPs), provides another way to restrain both initiator and effector caspases. XIAP has three N-terminal BIR domains; the one termed BIR2 binds to and inhibits:
#Question id: 1482
#Unit 4. Cell Communication and Cell Signaling
XIAP-mediated inhibition relieved by:
#Question id: 1483
#Unit 4. Cell Communication and Cell Signaling
The apoptosome serves as an activation machine for the:
#Question id: 1484
#Unit 4. Cell Communication and Cell Signaling
DNA damage or ultraviolet irradiation leads to induction of synthesis of the BH3-only, termed as:
#Question id: 1485
#Unit 4. Cell Communication and Cell Signaling
The presence of specific trophic factors (e.g., NGF) leads to activation of their cognate receptor tyrosine kinases (e.g., TrkA) and activation of :
#Question id: 1486
#Unit 4. Cell Communication and Cell Signaling
Removal of a cell from its substratum disrupts integrin signaling, leading to release of the BH3-only protein from the cytoskeleton, known as: