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TLS Online TPP Program
#Question id: 12179
#Unit 2. Cellular Organization
Match the following human ABC proteins (Column I) with their function (Column II)
Which of the following is correct?
TLS Online TPP Program
#Question id: 12180
#Unit 2. Cellular Organization
Following statements are regarding to cotransport.
A. The two forces constituting the electrochemical gradient—the membrane electric potential and the ion concentration gradient—may act in the same or opposite directions.
B. Cotransporters use the energy released by movement of an ion (usually H+ or Na+) down its electrochemical gradient to power the import or export of a small molecule or different ion against its concentration gradient.
C. Cotransporters use the energy released by movement of an ion (usually H+ or Na+) down its electrochemical gradient to power the import or export of a small molecule or different ion down its concentration gradient.
D. The cells lining the small intestine and kidney tubules contain symporters that couple the energetically favorable entry of Na+ to the import of glucose against its concentration gradient.
Which of the following is incorrect?
TLS Online TPP Program
#Question id: 12181
#Unit 2. Cellular Organization
Following statements are regarding to the CFTR.
A. cystic fibrosis transmembrane conductance regulator allows Cl− ions to flow out of the cell, following their concentration gradient.
B. ATP binding to CFTR’s two nucleotide-binding domains appears to close the Cl− channel, and the hydrolysis of one ATP opens it (the other ATP remains intact).
C. the CFTR channel can open only if its regulatory domain (which is unique among ABC transporters) has been phosphorylated, thus regulating the flow of ions across the membrane.
D. The maintenance of electrical neutrality requires that the Cl− ions transported by the CFTR be accompanied by positively charged ions, mainly Na+. The transported ions are osmotically accompanied by water, thus maintaining the proper level of fluidity in secretions of the airways, intestinal tract, and the ducts of the pancreas, testes, and sweat glands.
Which of the following combination is correct?
TLS Online TPP Program
#Question id: 12182
#Unit 2. Cellular Organization
The cell cycle is controlled by protein kinases that comprise a catalytic subunit and a regulatory subunit. Which of the following statement is correct regarding to these subunits?
TLS Online TPP Program
#Question id: 12183
#Unit 1. Molecules and their Interaction Relevant to Biology
Following statements are regarding to regulation of S phase and mitotic cyclin levels in budding yeast.
A. In late anaphase, the anaphase-promoting complex (APC/C) ubiquitinylates S phase and mitotic cyclins.
B. In late anaphase, the anaphase-promoting complex (APC/C) phosphorylates S phase and mitotic cyclins.
C. During exit from mitosis and G1, Cdh1 is dephosphorylated and active; during S phase and mitosis, Cdh1 is phosphorylated and dissociates from APC/C, and APC/C becomes inactive.
D. During exit from mitosis and G1, Cdh1 is phosphorylated and active; during S phase and mitosis, Cdh1 is dephosphorylated and dissociates from APC/C, and APC/C becomes inactive.
E. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, phosphorylate Cdh1 at the G1–S phase transition.
F. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, ubiquitinylates Cdh1 at the G1–S phase transition.
Which of the following combination is correct?
TLS Online TPP Program
#Question id: 12183
#Unit 2. Cellular Organization
Following statements are regarding to regulation of S phase and mitotic cyclin levels in budding yeast.
A. In late anaphase, the anaphase-promoting complex (APC/C) ubiquitinylates S phase and mitotic cyclins.
B. In late anaphase, the anaphase-promoting complex (APC/C) phosphorylates S phase and mitotic cyclins.
C. During exit from mitosis and G1, Cdh1 is dephosphorylated and active; during S phase and mitosis, Cdh1 is phosphorylated and dissociates from APC/C, and APC/C becomes inactive.
D. During exit from mitosis and G1, Cdh1 is phosphorylated and active; during S phase and mitosis, Cdh1 is dephosphorylated and dissociates from APC/C, and APC/C becomes inactive.
E. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, phosphorylate Cdh1 at the G1–S phase transition.
F. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, ubiquitinylates Cdh1 at the G1–S phase transition.
Which of the following combination is correct?