TLS Online TPP Program

#Question id: 32324


If malate is converted to fumarate with standard free change 3 kJ/mol then this reaction is

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. Reversible with Keq = 1
  2. Irreversible with Keq = 2
  3. Irreversible with Keq = 100
  4. Reversible with Keq = 0.30
More Questions
TLS Online TPP Program

#Question id: 2980

#Unit 2. Cellular Organization

Following statements are regarding to the protein phosphatase Cdc14 function in budding yeast.

A. In budding yeast, the protein phosphatase Cdc14 throws the switch between two mutually antagonistic states during anaphase.

B. Cdc14 is kept inactive during most of the cell cycle, but is activated during anaphase by a GTPase signaling pathway known as the mitotic exit network.

C. Mitotic exit network is unresponsive to spindle position and becomes active in anaphase.

D. Cdc14 phosphatase activated by the activation of protein kinase cascade.

E. Cdc14 dephosphorylates APC/CCdh1 and Sic1 to promote mitotic cyclin degradation

and mitotic CDK inactivation, respectively. This process leads to exit from mitosis.

Which of the following combination is incorrect?

TLS Online TPP Program

#Question id: 2981

#Unit 2. Cellular Organization

For the nuclear envelope to be broken down as cells go from prophase to prometaphase during mitosis, the nuclear lamina has to be disassembled. Which of the following statement is incorrect?

TLS Online TPP Program

#Question id: 2982

#Unit 2. Cellular Organization

Match the following proteins (Column I) with their functions (Column II) during cell cycle.

Column I

Column II

A. Cdc25C phosphatase

i. Activates vertebrate S phase CDKs

B. INK4

ii. Activation of Mitotic CDKs

C. Cdc25A phosphatase

iii. Binds and inhibits G1 CDKs

D. APC/CCdc20

iv. Degradation of securin

TLS Online TPP Program

#Question id: 2983

#Unit 2. Cellular Organization

Cell cycle is regulated by master regulators (cyclin and CDKs). In vertebrates, G1 CDK activity rises during G1 and is stimulated by the presence of growth factors. When signaling from growth factors is sustained, the resulting cyclin D–CDK4/6 complexes begin phosphorylating Rb, releasing some E2F, which stimulates transcription of the genes encoding cyclin E, CDK2, and E2F itself. In a particular cell type there is a mutation in Rb such that it cannot be phosphorylated. What will be the correct expression pattern of cyclin E in these cells after mitotic stimulation?

TLS Online TPP Program

#Question id: 2984

#Unit 2. Cellular Organization

Certain unicellular eukaryotes, including diatoms and some yeasts, have mechanisms of nuclear division that may resemble intermediate steps in the evolution of mitosis. Which of the following is a characteristic feature of nuclear division in these organisms?

TLS Online TPP Program

#Question id: 2985

#Unit 2. Cellular Organization

Use the figure to answer the question below. The unlettered circle at the top of the figure shows a diploid nucleus with four chromosomes that have not yet replicated. There are two pairs of homologous chromosomes, one long and the other short. One haploid set is black, and the other is gray. The circles labeled A to E show various combinations of these chromosomes. What is the correct chromosomal condition for one daughter nucleus at telophase of mitosis?