TLS Online TPP Program

#Question id: 32331


Following statements about actin filament assembly are correct EXCEPT:

#Unit 2. Cellular Organization
  1. Actin can reversibly assemble into filaments that consist of two helices of actin subunits.
  2. Within the filament, the subunits are positioned with their nucleotide-binding cleft directed toward the plus end.
  3. As the concentration of actin monomers declines, the system approaches a steady state.
  4. The lag phase in filament growth is eliminated if preexisting seeds are added to the solution.
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TLS Online TPP Program

#Question id: 3824

#Unit 3. Fundamental Processes

State whether the following statements is true/false regarding DNA replication.

1. The polymerization of DNA is essentially irreversible due to the hydrolysis of pyrophosphate.

2. On average about twenty errors are made during each replication of the human genome.

3. DNA polymerase I possesses 5ʹ → 3ʹ exonuclease activity.

4. All DNA ligase enzymes use ATP as a cosubstrate.

5. The purpose of SSB is to prevent single-stranded DNA from folding back on itself to form double-helical regions.

TLS Online TPP Program

#Question id: 3825

#Unit 3. Fundamental Processes

Telomeres are the repetitive sequence of T's and G's that are present in the eukaryotes to protect the random cleavage from nucleases. These telomeres are synthesized by the enzyme telomerase. Which of the following are the properties of enzyme telomerase?

TLS Online TPP Program

#Question id: 3826

#Unit 3. Fundamental Processes

Which scientists first gave experimental evidence that DNA is the genetic material?

TLS Online TPP Program

#Question id: 3827

#Unit 3. Fundamental Processes

It takes about the same amount of time for eukaryotic chromosomes to be replicated in vivo as it does for E. coli. Why is this true?

TLS Online TPP Program

#Question id: 3828

#Unit 3. Fundamental Processes

Why does E. coli need both DNA polymerase III and DNA polymerase I?

TLS Online TPP Program

#Question id: 3829

#Unit 3. Fundamental Processes

Why is only one copy of DNA made per cell division cycle in eukaryotes despite the presence of multiple origins of replication?