TLS Online TPP Program

#Question id: 32374


What does the pyrene-actin polymerization assay specifically measure?

#Unit 2. Cellular Organization
  1. Actin filament length
  2. Total actin concentration
  3. The rate of actin filament assembly over time
  4. The localization of actin filaments in cells
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TLS Online TPP Program

#Question id: 1367

#Unit 4. Cell Communication and Cell Signaling

Match the following junctions (column A) with their intracellular adaptors (column B).

Column A

Column B

A. Adherens junctions

I. Plectin, dystonin

B. Desmosomes

II. ZO-1,2,3

C. Hemidesmosomes

III. Catenins, vinculin

D. Gap junctions

IV. Plakoglobin, plakophilins

TLS Online TPP Program

#Question id: 1368

#Unit 4. Cell Communication and Cell Signaling

The following statements are made with reference to the characteristic of proteoglycans (major constituents of ECM). Which one of them is incorrect?

TLS Online TPP Program

#Question id: 1369

#Unit 4. Cell Communication and Cell Signaling

The following statements are made with reference to characteristics of glycosaminoglycans and proteoglycans, which are major constituents of extracellular matrix. Which one of them is incorrect?

TLS Online TPP Program

#Question id: 1370

#Unit 4. Cell Communication and Cell Signaling

H. V. Wilson worked with sponges to gain some insight into exactly what was responsible for holding adjacent cells together. He exposed two species of differently pigmented sponges to a chemical that disrupted intercellular junctions, and the cells of the sponges dissociated. Wilson then mixed the cells of the two species and removed the chemical that caused the cells to dissociate. Wilson found that the sponges reassembled into two separate species. The cells from one species did not interact or form associations with the cells of the other species.

How do you explain the results of Wilson's experiments?

TLS Online TPP Program

#Question id: 1371

#Unit 4. Cell Communication and Cell Signaling

A researcher was studying a protein ‘A’ which has been observed to move across cells when an extracellular electrical stimulus is provided. An artificial peptide ‘Z’ was prepared which resembles the structure of pannexins and competitively inhibits pannexon formation. Which one of the following statements will best explain the fate of protein ‘A’ if, the cells are treated with peptide ‘Z’ and then, electrical stimulus is provided.

TLS Online TPP Program

#Question id: 1372

#Unit 4. Cell Communication and Cell Signaling

Match the following junctions (Column I) with their functions (Column II).

Column I

Column II

a. adherens junctions

i. Controlling solute flow, signaling

b. gap junctions

ii. Shape, rigidity, signaling

c. tight junctions

iii. Shape, tension, signaling, force transmission

d. hemidesmosomes

iv. Communication, small-molecule transport

between cells