#Question id: 1523
#Unit 4. Cell Communication and Cell Signaling
Following statements are regarding to the apoptosis which is induced by trophic factors.
A. The presence of specific trophic factors (e.g., NGF) leads to activation of their cognate receptor tyrosine kinases (e.g., TrkA) and activation of the PKB pathway.
B. DNA damage or ultraviolet irradiation leads to induction of synthesis of the BH3-only Puma protein. Puma binds to Bak and Bax as well as to Bcl-2, allowing Bak and Bax to form oligomeric pores.
C. Removal of a cell from its substratum disrupts integrin signaling, leading to release of the BH3-only Bim protein from the cytoskeleton.
D. Binding of extracellular death signals, such as tumor necrosis factor and Fas ligand, to their receptors oligomerizes an associated protein (FADD), which in turn triggers the caspase cascade, leading to cell murder by apoptosis.
Which of the following pathway does not belong to the trophic factor inducing apoptotic pathway?
#Question id: 15956
#Unit 12. Applied Biology
#Question id: 27029
#Unit 10. Ecological Principles
#Question id: 2208
#Unit 2. Cellular Organization
Which of the following statements is a reasonable explanation for why unsaturated fatty acids help keep a membrane more fluid at lower temperatures?
#Question id: 12659
#Unit 7. System Physiology – Animal