TLS Online TPP Program
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TLS Online TPP Program
#Question id: 33359
#Unit 1. Molecules and their Interaction Relevant to Biology
The protein calcineurin binds to the protein calmodulin with an association rate of 8.9 X103 M-1s-1 and an overall dissociation constant, Kd, of 10 nM. The dissociation rate, kd
TLS Online TPP Program
#Question id: 33360
#Unit 1. Molecules and their Interaction Relevant to Biology
a. HbS (sickle-cell Hb): substitutes a Val for a Glu on the surface
b. Hb Cowtown: eliminates an ion pair involved in T-state stabilization
c. Hb Memphis: substitutes one uncharged polar residue for another of similar size on the surface
d. Hb Bibba: substitutes a Pro for a Leu involved in an α helix
Which Hb variant least likely to cause pathological symptoms
TLS Online TPP Program
#Question id: 33361
#Unit 1. Molecules and their Interaction Relevant to Biology
a. Hb Cowtown: eliminates an ion pair involved in T-state stabilization
b. Hb Milwaukee: substitutes a Glu for a Val
c. Hb Providence: substitutes an Asn for a Lys that normally projects into the central cavity of the tetramer
d. Hb Philly: substitutes a Phe for a Tyr,
Which Hb variant will not bind to BPG
TLS Online TPP Program
#Question id: 33362
#Unit 1. Molecules and their Interaction Relevant to Biology
a. Hb Cowtown: eliminates an ion pair involved in T-state stabilization
b. Hb Milwaukee: substitutes a Glu for a Val
c. Hb Providence: substitutes an Asn for a Lys that normally projects into the central cavity of the tetramer
d. Hb Philly: substitutes a Phe for a Tyr
Which Hb variant will have changed pI as compared to HbA
TLS Online TPP Program
#Question id: 33363
#Unit 1. Molecules and their Interaction Relevant to Biology
An antibody binds to an antigen with a Kd of 5 X10-8 M. At what concentration of antigen will θ be 0.2
TLS Online TPP Program
#Question id: 33364
#Unit 1. Molecules and their Interaction Relevant to Biology
An antibody binds to an antigen with a Kd of 5 X10-8 M. At what concentration of antigen will θ be 0.5