Which of following statement is/are correct

A. Some weak interactions are formed in the ES complex, 

B. Full complement of such interactions between substrate and enzyme is formed only when the substrate reaches the transition state.

C. Induced fit model best explains binding of substrate in transition state

D. Binding energy concept of catalysed reaction is best suits to induced fit model

#Question id: 10304

#Unit 6. System Physiology – Plant

Pyruvate is coverted into the Acetyl-CoA, Acetyl-CoA contain the acetyl group which are comes from the pyruvate and Coenzyme A (CoA) that contain other groups such as;

a) A reactive thiol (—SH) group that is critical to the role of CoA as an acyl carrier in a number of metabolic reactions

b) contain pantothenic acid,  A hydroxyl group of pantothenic acid is joined to a modified ADP moiety by a phosphate ester bond

c) pantothenic acid carboxyl group is attached to β-mercaptoethylamine in amide linkage

d) Hydroxyl group at the 3’ position of the ADP moiety has a phosphoryl group not present in free ADP

which of the following correct observation about Coenzyme A (CoA)?

#Question id: 10305

#Unit 6. System Physiology – Plant

Pyruvate dehydrogenase complex Consists of three Distinct enzymes and it requires Coenzymes, these are;

#Question id: 10306

#Unit 6. System Physiology – Plant

pyruvate dehydrogenase (PDH) complex requires five different coenzymes or prosthetic groups and these enzymesalso require four different vitamins in human nutrition are vital components of this system:

#Question id: 10307

#Unit 6. System Physiology – Plant

pyruvate dehydrogenase (PDH) complex requires many enzymes for their functions, which of the following enzyme are not the part of this complex?

#Question id: 10308

#Unit 6. System Physiology – Plant

Oxidative decarboxylation of pyruvate to acetyl-CoA by the PDH complex, how the pyruvate dehydrogenase complex carries out the five consecutive reactions in the decarboxylation and dehydrogenation of pyruvate?

 A) Pyruvate reacts with the bound thiamine pyrophosphate (TPP) of pyruvate dehydrogenase, undergoing decarboxylation to the hydroxyethyl derivative

 B) A transesterification in which the —SH group of CoA replaces the —SH group of E2 to yield acetyl-CoA and the fully reduced (dithiol) form of the lipoyl group

 C) The reduced FADH2 of E3 transfers a hydride ion to NAD1 , forming NADH, the enzyme complex is now ready for another catalytic cycle

 D) The transfer of two electrons and the acetyl group from TPP to the oxidized form of the lipoyllysyl group of the core enzyme, dihydrolipoyl transacetylase, to form the acetyl thioester of the reduced lipoyl group

 E) Dihydrolipoyl dehydrogenase promotes transfer of two hydrogen atoms from the reduced lipoyl groups of E2 to the FAD prosthetic group of E3 , restoring the oxidized form of the lipoyllysyl group of E2

 Find out the correct sequence of action of this complex enzyme?

#Question id: 10309

#Unit 6. System Physiology – Plant

Which of the following carbon compound also called the oxoglutarate?