TLS Online TPP Program

#Question id: 33232


In RNase A 

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. His12 acts as generalized base which abstract proton from 2’OH of sugar.
  2. His119 acts as generalized base which abstract proton from 2’OH of sugar.
  3. 2’-3 cyclic intermediate is dissolved by His12
  4. His12 acts as generalized acid which abstract proton from 2’OH of sugar.
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TLS Online TPP Program

#Question id: 33481

#Unit 2. Cellular Organization

A. In homologous introns, the pattern of divergence involves both changes in length.
B. Divergence in introns is due to deletions and insertions and base substitutions. 
C. Introns are slowly evolve while exons much more rapidly 
D. When a gene is compared among different species, there are instances where its exons are homologous but its introns have diverged so much that very little homology is retained.

TLS Online TPP Program

#Question id: 33482

#Unit 2. Cellular Organization

Find true and false statements
A. In general, mutations occur at the same rate in both exons and introns, 
B. Exon mutations are eliminated more effectively by selection.
C. Introns may more freely accumulate point substitutions and other changes.

TLS Online TPP Program

#Question id: 33483

#Unit 2. Cellular Organization

Which of the following is correct
A. A set of homologous genes should share common features that preceded their evolutionary separation.
B. All globin genes have a common form of organization with four exons and one introns.
C. A gene family is defined as a group of genes that encode related or identical products as a result of gene-duplication events.

TLS Online TPP Program

#Question id: 33484

#Unit 2. Cellular Organization

When a complete gene is found within the intron of a larger “host” gene called as

TLS Online TPP Program

#Question id: 33485

#Unit 2. Cellular Organization

Most genes are uninterrupted in yeast, but most genes are interrupted in flies and mammals. Uninterrupted genes have

TLS Online TPP Program

#Question id: 33486

#Unit 2. Cellular Organization

Only a few genes have uninterrupted coding sequences in case of mammals. How much % of genes in mammals are uninterrupted