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#Unit 3. Fundamental Processes
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#Unit 10. Ecological Principles
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#Question id: 4484
#Unit 3. Fundamental Processes
Match General Transcription Factors with their functions;
i. TAFs |
A. Appears to regulate the binding of TBP to DNA. It does this using an inhibitory flap that binds to the DNA-binding surface of TBP, another example of molecular mimicry. This flap must be displaced for TBP to bind TATA. |
ii. TFIIB |
B. Insert into the RNA-exit channel and active center cleft of Pol II in a manner analogous to the sigma region 3/4 linker in the bacterial case. |
iii. TFIIH |
C. As an ATP-driven translocator of double-stranded DNA. |
iv. TFIIF |
D. This two-subunit (in humans) factor associates with Pol II and is recruited to the promoter together with that enzyme. |