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TLS Online TPP Program

#Question id: 7127

The immunoglobulin genes are expressed in B-cells, and the b-globin gene is expressed in red blood cells. What manipulations might be carried out to get the b-globin gene to be expressed in B-cells?

#Unit 5. Developmental Biology
  1. The coding region of an immunoglobulin gene could be combined with the cis-regulatory region of the b-globin genes, and this artificial gene would then express b-globin in B-cells.
  2. The cis-regulatory region of the b-globin gene could be inserted into B-cells, which would then express their own version of the b-globin gene.
  3. The cis-regulatory region of an immunoglobulin gene could be combined with the coding region of the b-globin genes, and this artificial gene would then express b-globin in B-cells.

  4. The transcription factors GATA-1 and GATA-2 (which activate the b-globin gene in erythrocytes) could be introduced into B-cells, which would then express their own copy of the b-globin gene.

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TLS Online TPP Program

#Question id: 5061

#Unit 5. Developmental Biology

 The activin family, the bone morphogenetic proteins (BMPs), the Nodal proteins, the Vg1 family included in-
TLS Online TPP Program

#Question id: 5062

#Unit 5. Developmental Biology

Which of the signaling pathway is represent in this figure?
TLS Online TPP Program

#Question id: 5063

#Unit 5. Developmental Biology

 ______ required to maintain ES cells in an undifferentiated state.
TLS Online TPP Program

#Question id: 5064

#Unit 5. Developmental Biology

Fibroblast growth factors, epidermal growth factors, platelet-derived growth factors, and stem cell factor are all paracrine factors that bind to
TLS Online TPP Program

#Question id: 5065

#Unit 5. Developmental Biology

Binding to the phosphorylated RTK through one of the RTK’s cytoplasmic domains, the adaptor protein also activates Ras. The activated receptor stimulates the adaptor protein to activate the:
TLS Online TPP Program

#Question id: 5066

#Unit 5. Developmental Biology

 The mutations of RAS that make it oncogenic by