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TLS Online TPP Program

#Question id: 7127

The immunoglobulin genes are expressed in B-cells, and the b-globin gene is expressed in red blood cells. What manipulations might be carried out to get the b-globin gene to be expressed in B-cells?

#Unit 5. Developmental Biology
  1. The coding region of an immunoglobulin gene could be combined with the cis-regulatory region of the b-globin genes, and this artificial gene would then express b-globin in B-cells.
  2. The cis-regulatory region of the b-globin gene could be inserted into B-cells, which would then express their own version of the b-globin gene.
  3. The cis-regulatory region of an immunoglobulin gene could be combined with the coding region of the b-globin genes, and this artificial gene would then express b-globin in B-cells.

  4. The transcription factors GATA-1 and GATA-2 (which activate the b-globin gene in erythrocytes) could be introduced into B-cells, which would then express their own copy of the b-globin gene.

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TLS Online TPP Program

#Question id: 28647

#Unit 2. Cellular Organization

G1/S phase CDKs and S phase CDKs, prevents reloading of MCM helicases by____
TLS Online TPP Program

#Question id: 28648

#Unit 2. Cellular Organization

Which of the following are the MCM helicase loading factors?
TLS Online TPP Program

#Question id: 28649

#Unit 2. Cellular Organization

Geminin a small protein, what is the contribution of geminin in cell cycle?
TLS Online TPP Program

#Question id: 28650

#Unit 2. Cellular Organization

Geminin is expressed in which of the following phase of cell cycle? 
TLS Online TPP Program

#Question id: 28651

#Unit 2. Cellular Organization

 A protein Geminin is binds to some type of factor in late G1 and inhibit it, which specifically involve to loading of the MCM helicase?
TLS Online TPP Program

#Question id: 28652

#Unit 2. Cellular Organization

Which of the ubiquitinylated ligase protein complexes recognized the N-terminus of a geminin protein destruction box that leads to degradation by proteosome in late anaphase?