How many reducing equivalents are produced during oxidation of one molecule of Palmitic acid

TLS Online TPP Program

#Question id: 15816

#Unit 8. Inheritance Biology

You and your lab partner have isolated 20 new mutant yeast strains that are defective in synthesis of threonine, an amino acid. These Thr- mutants do not grow on minimal medium, but they do grow on minimal medium supplemented with threonine. Ten of your Thr- mutants (numbered 1 through 10) were isolated in a strain of mating type a (MAT a). The other 10 Thrmutants (numbered 11 through 20) were isolated in a strain of mating type α (MAT α). You and your lab partner cross each of the MAT a strains to each of the MAT α strains, and you include crosses to the appropriate wild-type strains. Your experimental observations are shown in the table below, where (-) indicates diploids that did not grow on minimal medium and (+) indicates diploids that did grow on minimal medium.

Which mutations do you know to be in the same gene?

TLS Online TPP Program

#Question id: 15820

#Unit 8. Inheritance Biology

Your friends Ben and Jane are contemplating having children and seek your genetic counsel. Ben and Jane are unrelated, but both have younger brothers with the same, extremely rare genetic trait. (In fact, Ben and Jane met at a support group meeting for children and families of children with this rare disorder.) Ben’s parents and Jane’s parents are all unaffected.          

Assume that the trait is autosomal recessive with complete penetrance. What is the probability that Ben and Jane’s first child will be affected with the trait? If not affected, what is the probability that the child is a carrier?

TLS Online TPP Program

#Question id: 15821

#Unit 8. Inheritance Biology

Your friends Ben and Jane are contemplating having children and seek your genetic counsel. Ben and Jane are unrelated, but both have younger brothers with the same, extremely rare genetic trait. (In fact, Ben and Jane met at a support group meeting for children and families of children with this rare disorder.) Ben’s parents and Jane’s parents are all unaffected.          

Assume that the trait is autosomal recessive with 80% penetrance. What is the probability that Ben and Jane’s first child will be affected?

TLS Online TPP Program

#Question id: 15831

#Unit 8. Inheritance Biology

Your friends Ben and Jane are contemplating having children and seek your genetic counsel. Ben and Jane are unrelated, but both have younger brothers with the same, extremely rare genetic trait. (In fact, Ben and Jane met at a support group meeting for children and families of children with this rare disorder.) Ben’s parents and Jane’s parents are all unaffected.        

 Assume that the trait is X-linked recessive with complete penetrance. What is the probability that Ben and Jane’s first child will be affected? What is the probability that the first child will be a carrier? 

TLS Online TPP Program

#Question id: 15832

#Unit 8. Inheritance Biology

Your friends Ben and Jane are contemplating having children and seek your genetic counsel. Ben and Jane are unrelated, but both have younger brothers with the same, extremely rare genetic trait. (In fact, Ben and Jane met at a support group meeting for children and families of children with this rare disorder.) Ben’s parents and Jane’s parents are all unaffected.        

 Assume that the trait is autosomal dominant with 80% penetrance in heterozygotes and 100% penetrance in homozygotes. What is the probability that Ben and Jane’s first child will be affected? 

TLS Online TPP Program

#Question id: 18083

#Unit 8. Inheritance Biology

The interaction of selection and inbreeding in determining the incidence of autosomal recessive diseases. Consider a gene in which recessive mutations occur at a rate of 10^-5. Assume a selective disadvantage S of 0.4 in homozygotes for the recessive allele. Would q be expected to rise, fall, or remain unchanged during the first 10 generations after the cessation of inbreeding, Briefly justify your answer. What numerical value would q approach after thousands of generations with no inbreeding?