TLS Online TPP Program

#Question id: 7132


What happens if you introduce the gene myoD into fibroblast cells growing in culture?

#Unit 5. Developmental Biology
  1. The fibroblasts will express muscle-specific proteins, fuse, and form functional muscle in culture.
  2. Nothing will happen because fibroblasts are derived from a different cell population in the embryo than are the muscle precursors that respond to myoD.
  3. The fibroblasts will undergo apoptosis, due to the abnormal effects of myoD on their normal differentiation.
  4. myoD will activate expression of myogenin, but the muscle-specific genes will not be able to activate.