Recently, it was reported that adult, differentiated cells can be made to behave as pluripotent stem cells by the introduction of a few genes, one of which was Oct4. What was the rationale for this experiment?

#Question id: 848

#Unit 1. Structure and Function of Biomolecules

Which of the brain diseases is not caused by the misfolding of brain proteins in mammals

#Question id: 849

#Unit 1. Structure and Function of Biomolecules

The rigidity of the peptide unit and the restricted set of allowed phi and psi angles limits the number of structures accessible to the unfolded form sufficiently to allow:-

#Question id: 850

#Unit 1. Structure and Function of Biomolecules

The experimental inverse of protein structure prediction, has provided insights into protein folding and stability. Protein design attempts to construct an amino acid sequence that will form a structure such as a sandwich of β sheets or a bundle of α helices;

#Question id: 851

#Unit 1. Structure and Function of Biomolecules

Methods is the Rosetta program, formulated by David Baker. To satisfy the program’s computational needs, a volunteer network of ∼100,000 computers, known as Rosetta@home, provides the 500,000 or so hours of processing time required to generate a structure;

#Question id: 852

#Unit 1. Structure and Function of Biomolecules

.________ enzyme revealed the relation between the amino acid sequence of a protein and its conformation.

#Question id: 853

#Unit 1. Structure and Function of Biomolecules

In the presence of a large excess of _______ the disulfides (cystines) are fully converted into sulfhydryls (cysteines).