TLS Online TPP Program

#Question id: 7141


Engrailed comes to be expressed in posterior compartments during Drosophila embryogenesis; what is the consequence of engrailed activation of hedgehog (Hh) signaling from the posterior compartment of the wing disc?

#Unit 5. Developmental Biology
  1. Hh activates decapentaplegic (Dpp) signaling at the compartment boundary; Dpp then acts as a morphogen to pattern the development of veins in the wing blade.
  2. Hh signaling from the posterior compartment specifies the adjacent compartment as an anterior compartment.
  3. Hh signaling in the posterior compartment acts as a morphogen to pattern the posterior portion of the wing.
  4. Hh signaling controls the identity of the Imaginal discs, in this case, specifying the disc as the wing disc.
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TLS Online TPP Program

#Question id: 3216

#Unit 11. Evolution and Behavior

The frequency of galactosemia is approximately 1 in 40,000 live births. The frequency of the carrier state can be calculated as

TLS Online TPP Program

#Question id: 3250

#Unit 11. Evolution and Behavior

Consider a diploid population at Hardy-Weinberg equilibrium. For a locus with two alleles, the frequency of the A1A1, A1A2 and A2A2 genotype is 0.01, 0.18 and 0.81) Which of the following statement is correct?

TLS Online TPP Program

#Question id: 3251

#Unit 11. Evolution and Behavior

Looking at 3 allele per locus and following Hardy Weinberg equilibrium what will be the expected heterozygosity if q1=0.5, q2=0.3, q3=0.2

TLS Online TPP Program

#Question id: 3252

#Unit 11. Evolution and Behavior

 The unaffected brother of a cystic fibrosis affected girl is referred for genetic counseling. Assume that the population is in Hardy-Weinberg equilibrium. Which of the following is correct?  (Cystic fibrosis is an autosomes recessive inheritance with an incidence of 1 in 2500).

TLS Online TPP Program

#Question id: 3253

#Unit 11. Evolution and Behavior

In a population 64% individuals of 1000 population are affected with autosomes dominant diseased. How many individuals are expected carry at least one dominant allele?

TLS Online TPP Program

#Question id: 3254

#Unit 11. Evolution and Behavior

Consider a single locus with 2 alleles which are at Hardy-Weinberg equilibrium. If the frequency of the heterozygous genotypes is 0.42, what is the frequency of one homozygote in the population?