TLS Online TPP Program

#Question id: 33896


In hydroxyapatite column chromatography used during DNA reassociation studies, what is the principle behind the differential binding of single- and double-stranded DNA?

#Unit 2. Cellular Organization
  1. Charge differences between strands
  2. Differences in phosphate group availability for binding
  3. Size exclusion based on strand length
  4. Higher affinity of hydroxyapatite for uracil-containing strands