To analyze existing MARs that are bound to the matrix in vivo, what is correct order of method 

A. Chromosomal loops decondensed by extracting the chromatin proteins. 

B. Removal of the DNA loops by treatment with restriction nucleases

C. Amplification of MAR and sequencing

TLS Online TPP Program

#Question id: 31038

#Unit 4. Cell Communication and Cell Signaling

For most, but not all, RTKs, the weakly active kinase in each subunit is thought to phosphorylate a key  residue, known as:

TLS Online TPP Program

#Question id: 31039

#Unit 4. Cell Communication and Cell Signaling

Phosphorylation of tyrosine in activation loop leads to a conformational change in the activation loop that unblocks the kinase active site for either ATP or the substrate by:

Reducing the Kd 

Increasing the Kd

Reducing the affinity

Increasing the affinity

Which of the following combination is correct?

TLS Online TPP Program

#Question id: 31040

#Unit 4. Cell Communication and Cell Signaling

HER3 is an EGF receptor that can bind ligands but lacks:

TLS Online TPP Program

#Question id: 31041

#Unit 4. Cell Communication and Cell Signaling

Which of the following statement is incorrect regarding HER2?

TLS Online TPP Program

#Question id: 31042

#Unit 4. Cell Communication and Cell Signaling

Monomeric Ras proteins are GTPase “switch” proteins. Ras activation is accelerated by: 

TLS Online TPP Program

#Question id: 31043

#Unit 4. Cell Communication and Cell Signaling

An SH2 domain is able to bind to a short target sequence of polypeptide that contains: