A. When interphase nuclei are suspended in a solution of low ionic strength, they swell and rupture to release fibers of chromatin.

B. Individual nucleosomes can be obtained by treating chromatin with the endonuclease micrococcal nuclease

C. When chromatin is digested with MNase, the DNA is cleaved into integral multiples of a unit length can be Fractionated by gel electrophoresis reveals the “ladder”

D. With MNase more than 95% of nuclear DNA can be recovered in the form of the 200-bp ladder.

Choose true and false

TLS Online TPP Program

#Question id: 31179

#Unit 4. Cell Communication and Cell Signaling

Wnt proteins are signaling molecules secreted from the cell and are modified by linkage of a:  

TLS Online TPP Program

#Question id: 31180

#Unit 4. Cell Communication and Cell Signaling

Wnt proteins are modified by linkage of a monounsaturated fatty acid, to which of the following amino acid in the middle of the wnt protein? 

TLS Online TPP Program

#Question id: 31181

#Unit 4. Cell Communication and Cell Signaling

The principal signaling receptor for Wnt proteins is Frizzled (Fz), which contains: 

TLS Online TPP Program

#Question id: 31182

#Unit 4. Cell Communication and Cell Signaling

Wnt signaling receptor, Frizzled (Fz), shows similarity with: 

TLS Online TPP Program

#Question id: 31183

#Unit 4. Cell Communication and Cell Signaling

When a mouse retroviral DNA, the mammary tumor virus (MMTV) genome, became inserted near the Wnt-1 gene, the retrovirus LTR promoter, results: 

TLS Online TPP Program

#Question id: 31184

#Unit 4. Cell Communication and Cell Signaling

Which of the following are the central player in the canonical Wnt intracellular signal transduction pathway in vertebrates and in Drosophila respectively?