TLS Online TPP Program

#Question id: 34120


The dynamic nature of DNA binding to the histone core structure is important, because many DNA-binding proteins strongly prefer to bind to histone-free DNA. Such proteins can recognize their binding site only when it is released from the histone octamer or is contained in linker or nucleosome-free DNA.

Which of the following statement stands untrue for above fact

#Unit 2. Cellular Organization
  1. DNA-binding site for a given protein on nucleosome can be found anywhere on wrapped DNA
  2. A binding site near position 73 of the 147 bp tightly associated with a nucleosome is rarely accessible. 
  3. Binding sites near the ends (position 1 or 147) of the nucleosomal DNA are most frequently accessible.
  4. Mechanism of exposure is due to unwrapping of the DNA from the nucleosome, rather than to the DNA briefly coming off the surface of the histone octamer
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TLS Online TPP Program

#Question id: 2556

#Unit 2. Cellular Organization

Which of the following processes generates a proton-motive force in mitochondria?

TLS Online TPP Program

#Question id: 2557

#Unit 2. Cellular Organization

In liver cells, the inner mitochondrial membranes are about five times the area of the outer mitochondrial membranes. What purpose must this serve?

TLS Online TPP Program

#Question id: 2558

#Unit 2. Cellular Organization

A young dog has never had much energy. He is brought to a veterinarian for help, and she decides to conduct several diagnostic tests. She discovers that the dog's mitochondria can use only fatty acids and amino acids for respiration, and his cells produce more lactate than normal. Of the following, which is the best explanation of the dog's condition?

TLS Online TPP Program

#Question id: 2559

#Unit 2. Cellular Organization

Even though plants cells carry out photosynthesis, they still use their mitochondria for oxidation of pyruvate. Under what conditions will plant cell mitochondria be active in this process?

TLS Online TPP Program

#Question id: 2560

#Unit 2. Cellular Organization

In a liver cell detoxifying alcohol and some other poisons, the enzymes of the peroxisome remove hydrogen from these molecules and ________.

TLS Online TPP Program

#Question id: 2561

#Unit 2. Cellular Organization

Tay-Sachs disease is a human genetic abnormality that results in cells accumulating and becoming clogged with very large, complex, undigested lipids. Which cellular organelle is most likely defective in this condition?