TLS Online TPP Program

#Question id: 34137


Which of the following best explains why glucose uptake into liver cells continues in insulin-resistant states, even when skeletal muscle glucose uptake is impaired?

#Unit 7. System Physiology – Animal
  1. Liver cells express GLUT-4 transporters, which are activated by AMP-activated protein kinase (AMPK) during fasting.
  2. Liver cells use GLUT-2 transporters, which are insulin-dependent and respond to glucokinase activation.
  3. Liver cells express GLUT-2 transporters, which are insulin-independent and facilitate passive glucose uptake based on concentration gradient.
  4. Glucokinase in liver cells directly increases the number of GLUT-4 transporters in the plasma membrane, enhancing glucose uptake.
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TLS Online TPP Program

#Question id: 4460

#Unit 3. Fundamental Processes

During initial transcription, the active center of RNA polymerase is translocated forward relative to the DNA template and synthesizes short transcripts before aborting, then repeats this cycle until it escapes the promoter. Three models have been proposed to account for this;

i. Polymerase moves along the DNA.

ii. The front part of the enzyme moves along the DNA, but because of a flexible region within the enzyme, the back part of the enzyme can remain stationary at the promoter.

iii. The enzyme remains stationary and pulls the DNA into itself.

TLS Online TPP Program

#Question id: 4461

#Unit 3. Fundamental Processes

According to some experiments, during initial transcription, the polymerase remains stationary on the promoter, unwinds downstream DNA, and pulls that DNA into itself, which model is this?

TLS Online TPP Program

#Question id: 4462

#Unit 3. Fundamental Processes

Promoter escape is associated with the breaking of all interactions (at the given promoter) between;

TLS Online TPP Program

#Question id: 4463

#Unit 3. Fundamental Processes

___?____ is a way to store and mobilize energy during transcription initiation, and its release upon escape is what enables polymerase to break free of the promoter and dislodge s factor from the core.

TLS Online TPP Program

#Question id: 4464

#Unit 3. Fundamental Processes

Role of Gre factor;

TLS Online TPP Program

#Question id: 4465

#Unit 3. Fundamental Processes

Main function of Nus proteins in transcription,