TLS Online TPP Program

#Question id: 34168


Angiotensin II stimulates aldosterone production in the zona glomerulosa by binding to AT1 receptors. Which of the following best describes the intracellular signaling pathway and its role in aldosterone biosynthesis?

#Unit 7. System Physiology – Animal
  1. AT1 activates cAMP via Gs protein, enhancing 11β-hydroxylase activity for cortisol synthesis
  2. AT1 activates adenylyl cyclase, increasing cAMP and PKA, which upregulates LDL receptor expression
  3. AT1 signals through Gq, activating phospholipase C, which increases PKC activity and promotes aldosterone synthase function
  4. AT1 signals via Gi protein to inhibit cAMP and reduce cortisol feedback, indirectly promoting aldosterone release
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TLS Online TPP Program

#Question id: 4466

#Unit 3. Fundamental Processes

As well as synthesizing the transcript, RNA polymerase performs two proofreading functions on that growing transcript;

i. Pyrophosphorolytic editing

ii. Hydrolytic editing

Choose correct processes accordingly,

A. The polymerase backtracks by one or more nucleotides and cleaves the RNA product, removing the error-containing sequence.

B. In this, the enzyme uses its active site, in a simple back-reaction,

C. Catalyze the removal of an incorrectly inserted ribonucleotide, by reincorporation of PPi

D. The enzyme can then incorporate another ribonucleotide in its place in the growing RNA chain.

TLS Online TPP Program

#Question id: 29016

#Unit 11. Evolution and Behavior

A recessive allele (a) that causes a genetic disease has a frequency (q) of 0.04. If the population mates randomly (F = 0.36), then how much proportion of lethality is increase due to inbreeding?

TLS Online TPP Program

#Question id: 12401

#Unit 6. System Physiology – Plant

IAA enters the cell either passively in the undissociated form (IAAH) or by transporter in the anionic form (IAA-) , which one of the following  transporter are involved in influx of the anionic form of auxin?

TLS Online TPP Program

#Question id: 23581

#Unit 13. Methods in Biology

Which of the following is false?

TLS Online TPP Program

#Question id: 27574

#Unit 1. Molecules and their Interaction Relevant to Biology

Misplaced Dispersion forces are responsible for

a. Sickle-Cell Anemia

b. Alzheimer's disease

c. CFTR

d. Huntington disease

Choose which of the above set of diseased caused by Misplaced Dispersion