TLS Online TPP Program

#Question id: 34168


Angiotensin II stimulates aldosterone production in the zona glomerulosa by binding to AT1 receptors. Which of the following best describes the intracellular signaling pathway and its role in aldosterone biosynthesis?

#Unit 7. System Physiology – Animal
  1. AT1 activates cAMP via Gs protein, enhancing 11β-hydroxylase activity for cortisol synthesis
  2. AT1 activates adenylyl cyclase, increasing cAMP and PKA, which upregulates LDL receptor expression
  3. AT1 signals through Gq, activating phospholipase C, which increases PKC activity and promotes aldosterone synthase function
  4. AT1 signals via Gi protein to inhibit cAMP and reduce cortisol feedback, indirectly promoting aldosterone release
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TLS Online TPP Program

#Question id: 22023

#Unit 1. Structure and Function of Biomolecules

Choose the correct equation for Haldane reversible reaction

TLS Online TPP Program

#Question id: 22024

#Unit 1. Structure and Function of Biomolecules

Some of the statements regarding competitive inhibition are given below
a)  The effect of a competitive inhibitor depends on the inhibitor concentration, the substrate       concentration and the relative affinities of the substrate and the inhibitor for the enzyme.
b) if the substrate concentration is low, the degree of inhibition will be great.
c) the substrate concentration is high, then the degree of inhibition will be marked low
d) non-competitive inhibitor can combine with an enzyme molecule to produce a dead-end complex
Choose the incorrect statement

TLS Online TPP Program

#Question id: 22025

#Unit 1. Structure and Function of Biomolecules

The Lineweaver-Burk equation in the presence of a competitive inhibitor will be: and Lineweaver-Burk plot showing the effect of competitive inhibition are shown
       
                      
What will be the value of X and X’ for above graph

TLS Online TPP Program

#Question id: 22060

#Unit 1. Structure and Function of Biomolecules

Km can be calculated from two ways from Lineweaver-Burk equation, choose the most appropriate one

TLS Online TPP Program

#Question id: 28158

#Unit 1. Structure and Function of Biomolecules

competitive inhibition may be

a. linear

b. parabolic

c. hyperbolic

d. zig-zag

TLS Online TPP Program

#Question id: 31323

#Unit 1. Structure and Function of Biomolecules

  A plot of V/[S] versus V is generated for an enzyme catalyzed reaction, and a straight line is obtained. Which is incorrect