Which of the following is consistent with a model for aging in which stresses leading to DNA damage cause senescence and aging?

TLS Online TPP Program

#Question id: 19735

#Unit 3. Fundamental Processes

In mammals, six telomeric proteins (TRF1, TRF2, Rap1, TIN2, TPP1, and POT1) comprises a complex which of the following is incorrect regrarding these telomeric protein

a) TRF1, TRF2, Rap1, binds to double stranded of DNA

b) TIN2 does not binds to DNA at all

c) POT1 binds to the GT tail extended by telomerase

d) TIN2 interacts with the two duplex telomeric DNA-binding proteins TRF1 and TRF2 as well as with TPP1

TLS Online TPP Program

#Question id: 19736

#Unit 3. Fundamental Processes

Which of the following shelterin protein interacts with the two duplex telomeric DNA-binding proteins TRF1 and TRF2 as well as with TPP1

TLS Online TPP Program

#Question id: 19737

#Unit 3. Fundamental Processes

Choose the incorrect statement regarding telomerase 

TLS Online TPP Program

#Question id: 19738

#Unit 3. Fundamental Processes

For the synthesis of telomere by telomerase require Only 

TLS Online TPP Program

#Question id: 19739

#Unit 3. Fundamental Processes

Telomeric RNA component in yeast and human are encoded by

TLS Online TPP Program

#Question id: 19740

#Unit 3. Fundamental Processes

Choose the correct statement

a) Telomeric RNA component is encoded by TLC1 in yeast, and hTERC in humans

b) Telomeric RNA component is encoded by hTERC in yeast, and TLC1 in humans

c) Telomerase protein component with catalytic activity is encoded by EST2 in yeast, hTERT in humans

d) Telomerase protein component with catalytic activity is encoded by hTERT in yeast, EST2 in humans