TLS Online TPP Program

#Question id: 7156


Which of the following is consistent with a model for aging in which stresses leading to DNA damage cause senescence and aging?

#Unit 5. Developmental Biology
  1. The DAF-16 protein of C. elegans is involved in the activation of stress responses.
  2. Dietary restriction in mammals reduces the production of DNA-damaging free radicals in the mitochondria.
  3. Werner's syndrome is a premature aging illness, possibly caused by a defect in DNA repair.
  4. All of the above are consistent with a model for aging based on DNA damage.