TLS Online TPP Program

#Question id: 7158


If the nerve supply to a newt limb is severed before amputation, how will this affect regeneration?

#Unit 5. Developmental Biology
  1. It will have no effect, since regeneration involves growth of new muscle, bone, and connective tissue.
  2. Regeneration of most tissues will occur normally, but regeneration of the nerves will not occur.
  3. Outgrowth will occur, but the identity of the limb will be lost and normal proximo-distal patterning will not occur.
  4. A blastema will form but will not grow, and regeneration will fail.
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TLS Online TPP Program

#Question id: 1242

#Unit 4. Cell Communication and Cell Signaling

Rhodopsin, a light-sensitive GPCR whose role in vision is dependent on its phosphorylation status, is influenced in part by the protein arrestin.  Which of the following is TRUE with regard to rhodopsin and vision?

TLS Online TPP Program

#Question id: 1243

#Unit 4. Cell Communication and Cell Signaling

One form of receptor desensitization can be mediated by negative feedback involving phosphorylation of the receptor itself by a kinase activated downstream of a second messenger. The phosphorylated receptor likely:

TLS Online TPP Program

#Question id: 1244

#Unit 4. Cell Communication and Cell Signaling

Which type of experimental evidence shows that the intrinsic GTPase activity of the Gα subunit is important for terminating effector activation?

TLS Online TPP Program

#Question id: 1245

#Unit 4. Cell Communication and Cell Signaling

Many PTB-containing proteins act as docking sites for multiple proteins. If these proteins are involved in the RTK signal transduction pathway, they most likely:

TLS Online TPP Program

#Question id: 1246

#Unit 4. Cell Communication and Cell Signaling

An SH2-containing protein contains a mutation that changes its binding pocket such that tyrosine and phosphotyrosine bind with equal affinity. As a result, MEK activity:

TLS Online TPP Program

#Question id: 1247

#Unit 4. Cell Communication and Cell Signaling

Which of the following is NOT true about the role of adapter proteins in the activation of Ras by receptor tyrosine kinases?