TLS Online TPP Program

#Question id: 7160


How does the dose-dependence of retinoic acid treatment support the notion that a gradient of retinoic acid can act as a morphogen along the proximo-distal axis in the limb?

#Unit 5. Developmental Biology
  1. Treatment with high levels of retinoic acid causes a proximal blastema to be respecified as a distal blastema, and only distal structures are regenerated.
  2. Treatment with high levels of retinoic acid causes any blastema to form only distal structures.
  3. Treatment with high levels of retinoic acid causes any blastema to be respecified as a proximal blastema, but it will form only proximal structures.
  4. Treatment with high levels of retinoic acid causes a distal blastema to be respecified as a proximal blastema, and regeneration of a full limb may be initiated from proximal values.

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TLS Online TPP Program

#Question id: 4511

#Unit 3. Fundamental Processes

The proteins are not needed for the splicing reaction itself, because

TLS Online TPP Program

#Question id: 4512

#Unit 3. Fundamental Processes

Some pre-mRNAs can be spliced in more than one way. Thus, mRNAs containing different selections of exons can be generated from a given pre-mRNA, called

TLS Online TPP Program

#Question id: 4513

#Unit 3. Fundamental Processes

Different snRNPs recognize the same (or overlapping) sequences in the pre-mRNA at different stages of the splicing reaction, which two snRNPs recognizing the 5’ splice site

TLS Online TPP Program

#Question id: 4514

#Unit 3. Fundamental Processes

What is true about coactivators,

A. The coactivators act directly by binding to the DNA

B. The coactivators act indirectly—not by binding to the DNA

C. Are required for essential communication between the activators and the complex composed of Pol II.

D. Are required for essential communication between the and the basal (or general) transcription factors.

TLS Online TPP Program

#Question id: 4515

#Unit 3. Fundamental Processes

Transcription Activators are,

A. Known to facilitate transcription at hundreds of promoters,

B. Specific for a few promoters,

C. Sensitive to the binding of signal molecules,

D. Providing the capacity to activate or deactivate transcription in response to a changing cellular environment.

TLS Online TPP Program

#Question id: 4516

#Unit 3. Fundamental Processes

High mobility group (HMG) proteins

A. are a common type of architectural regulator

B. facilitating the looping of the DNA

C. the binding is relatively very specific

D. are abundant in chromatin and bind to DNA with limited specificity.