TLS Online TPP Program

#Question id: 7197


Following statements are regarding to PAR proteins and the establishment of polarity during early development in nematodes.

A. The internal cytoplasm contains PAR-3, PAR-6, and PKC-3, and the cortical cytoplasm contains PAR-2 and PAR-1.

B. PAR-3 and PAR-6, interacting with the protein kinase PKC-3 are uniformly distributed in the cortical cytoplasm. PKC-3 restricts PAR-1 and PAR-2 to the internal cytoplasm by phosphorylating them.

C. Once PAR-1 is in the cortical cytoplasm, it phosphorylates PAR-3, causing PAR-3 (and its binding partner, PKC-3) to leave the cortex.

D. During first cleavage, the metaphase plate is closer to the posterior, and the fertilized egg is divided into two cells, one having the anterior PARs (PAR-1 and PAR-2) and one having the posterior PARs (PAR-3 and PAR-6).

Which of the following statements are correct?

#Unit 5. Developmental Biology
  1. A and B
  2. B and C
  3. C and D
  4. A, B and C
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TLS Online TPP Program

#Question id: 12633

#Unit 6. System Physiology – Plant

In the absence of BRs, BRI1 and BAK1 can form inactive homodimers, which of the following activity is inhibited  these BRs receptor?

TLS Online TPP Program

#Question id: 12634

#Unit 6. System Physiology – Plant

During Brassinosteroid (BR) signal transduction pathway two forms exist,
1) In absence of Brassinolide
2) In presence of Brassinolide
a) BKI1 is phosphorylated and dissociates from the plasma membrane
b) BRI1 phosphorylation, and promotes BRI1–BAK1 heterodimerization, bringing their cytoplasmic domains together for interaction, transphosphorylation
c) BRI1 and BAK1 can form homodimers and both undergoes endocytosis and recycling
d) BIN2 kinases Phosphorylate transcriptional factor BES1 and BZR1 and these Phosphorylated proteins are shortlived and are degraded in the proteasome
e) BSK proteins activate BSU1 phosphatase which dephosphorylated BIN2 is degraded by the proteasome system
f) In absence of BIN2, dephosphorylated  transcriptional factor BES1 and BZR1 form heterodimers with different transcription factors and bind E-box sequences to activate genes.
Find out the correct match with in absence and presence of BL in BRs signal transduction pathway

TLS Online TPP Program

#Question id: 12635

#Unit 6. System Physiology – Plant

What is the role of BSK in Brassinosteroid signal transduction pathway?

TLS Online TPP Program

#Question id: 12636

#Unit 6. System Physiology – Plant

Which of the following is the correct prediction about Strigolactones?

TLS Online TPP Program

#Question id: 12637

#Unit 6. System Physiology – Plant

Strigolactones are synthesized from β-carotene , in which 9-cis-β-Carotene is coverted into the 9-cis-β-apo-10‘-carotenal by sequential cleavage  in the plastids by enzyme known as,

TLS Online TPP Program

#Question id: 12638

#Unit 6. System Physiology – Plant

strigolactone biosynthesis takes place , find the correct sequence of these signal transduction pathways;
a) D14* hydrolyses strigolactone and releases the products of hydrolysis. 
b) D14 disengages from the SCFMAX2 complex and returns to its original conformation, allowing it to respond to fresh strigolactone signal.
c) D14* interacts with the F-box protein MAX2 and the other partners of the SCFMAX2 ubiquitin ligase complex.
d) The α-/β-fold hydrolase D14 binds and reacts with strigolactone, changing its conformation to the active form, D14*
e) Target protein(s) are recognized by the D14*–SCFMAX2 complex and are ubiquitinated