Following statements are regarding to PAR proteins and the establishment of polarity during early development in nematodes.

A. The internal cytoplasm contains PAR-3, PAR-6, and PKC-3, and the cortical cytoplasm contains PAR-2 and PAR-1.

B. PAR-3 and PAR-6, interacting with the protein kinase PKC-3 are uniformly distributed in the cortical cytoplasm. PKC-3 restricts PAR-1 and PAR-2 to the internal cytoplasm by phosphorylating them.

C. Once PAR-1 is in the cortical cytoplasm, it phosphorylates PAR-3, causing PAR-3 (and its binding partner, PKC-3) to leave the cortex.

D. During first cleavage, the metaphase plate is closer to the posterior, and the fertilized egg is divided into two cells, one having the anterior PARs (PAR-1 and PAR-2) and one having the posterior PARs (PAR-3 and PAR-6).

Which of the following statements are correct?

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#Question id: 28943

#Unit 7. System Physiology – Animal

Hypothalamus secreting Corticotropin-releasing hormone (CRH) stimulates the secretion of____

TLS Online TPP Program

#Question id: 28944

#Unit 7. System Physiology – Animal

Which of the following Prediction is correct about adrenocorticotropic hormone (ACTH) ? 

a) CRH Stimulates secretion of ACTH by corticotropes

b) it controls the secretion of cortisol by the activation of adenylyl cyclase via Gαq

c) it controls the secretion of cortisol by the activation of adenylyl cyclase via Gαs

TLS Online TPP Program

#Question id: 28945

#Unit 7. System Physiology – Animal

Which of the following hormones is involved to promotes the mammary gland development and milk production?

TLS Online TPP Program

#Question id: 28946

#Unit 7. System Physiology – Animal

GnRH is carried to the anterior pituitary, stimulates the secretion of hormones by gonadotropes. these hormones are; 

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#Question id: 28947

#Unit 7. System Physiology – Animal

Kallmann syndrome exhibit gonadal dysfunctions in male, which of the following statements is incorrect ?

A. a condition that causes hypogonadotropic hypogonadism (HH) 

B. an impaired sense of smell called anosmia 

C. it causes due to the deficiency of gonadotropin-releasing hormone (GnRH) 

D. they have higher level of circulating gonadotropins

E. a condition that causes hypergonadotropic hypergonadism (HH)

TLS Online TPP Program

#Question id: 28948

#Unit 7. System Physiology – Animal

FSH and LH is involved to which of the following activity?