TLS Online TPP Program

#Question id: 7199


Following statements are regarding to the establishment of ventral axis in Drosophila.

A. Ventral follicle cells synthesize Pipe. Pipe signal sulfates ventral vitelline proteins.

B. GD cleaves Snake to its active form and forms a complex with Snake and uncleaved Easter proteins.

C. Sulfated vitelline membrane proteins bind Gastrulation-defective (GD).

D. Easter protein is cleaved into its active form. Cleaved Easter binds to and cleaves Spätzle; activated Spätzle binds to Toll receptor protein.

E. Dorsal protein enters the nucleus and ventralizes the cell.

F. Toll activation activates Tube and Pelle, which phosphorylate the Cactus protein. Cactus is degraded, releasing it from Dorsal.

Which of the following is the correct sequence?

#Unit 5. Developmental Biology
  1. (A)(B)(C) (D) (E) (F)
  2. (B) (A) (C) (F) ( D) (E)
  3. (A) (C) (B) (D) ( F) (E)
  4. (C) (B) (A) (D) (F) (E)