TLS Online TPP Program

#Question id: 7200


Following statements are regarding to Reaction-diffusion mechanism for proximal-distal limb specification. Which of the following statement is incorrect?

#Unit 5. Developmental Biology
  1. In the inhibitory domain immediately outside the AER, cells are kept dividing by FGFs and Wnts and are prevented from forming cartilage.
  2. In the active domain, each cell secretes but can not respond to activating paracrine factors of the TGF-β family (TGF-β, BMPs, activin) and cell adhesion factors such as galectin-1. These factors stimulate their own synthesis as well as that of the extracellular matrix and cell adhesion proteins that promote aggregation.
  3. The activating cells also stimulate the synthesis of diffusible inhibitors of aggregation (including Noggin and galectin-8), preventing cell adhesion in neighboring regions.

  4. A third domain, the “frozen zone” well beyond the influence of the AER, contains the formed cartilage primordia of the skeleton at proximal regions of the developing limb.
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TLS Online TPP Program

#Question id: 23257

#Unit 13. Methods in Biology

Centromeric probes are useful in identifying 

TLS Online TPP Program

#Question id: 23258

#Unit 13. Methods in Biology

If the probes are hybridized at the ends of the chromosome then they are called as

TLS Online TPP Program

#Question id: 23279

#Unit 13. Methods in Biology

What will be the value of D if sin angle is 90o and oil immersion is used at λ=700?

TLS Online TPP Program

#Question id: 23285

#Unit 8. Inheritance Biology

Chromosome are classified into four basic term, 

 

          Chromosome      

 

 

A) Metacentric chromosome

 

i) centromeres present at the end of the chromosome

 

B) Submetacentric chromosome

 

ii) chromomere near the end of the chromosomes

 

C) Acrocentric chromosome

 

iii) Centromere in the middle of the chromosome and divides the chromosome into two equal arms.

 

D) Telocentric chromosome

 

iv) The centromere is present near the middle and divides the chromosome into two unequal arms

TLS Online TPP Program

#Question id: 23286

#Unit 8. Inheritance Biology

Individual chromosomes may lose or gain parts and the order of genes within a chromosome may become altered. These variations in the number and structure of chromosomes are termed as

TLS Online TPP Program

#Question id: 23287

#Unit 8. Inheritance Biology

Chromosome mutations can be grouped into three basic categories:
I) Chromosome rearrangements
II) Aneuploidy
III) Polyploidy
these mutation alters the number and structure of chromosomes such as,
 a) One or more individual chromosomes are added or deleted
b) The loss of a chromosomal segment
c) A piece of a chromosome might be duplicated, deleted, or inverted
d) One or more complete sets of chromosomes are added
e) In which one or more copies of a DNA segment is produced
Find out the correct pairing of chromosomal mutations,