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#Question id: 7209


Following statements are related to the Epigenetic regulation of Hox gene expression in the chick limb .

A. Hoxa13 is normally not expressed during early limb bud outgrowth.

B. Hoxa13 is normally expressed during early limb bud outgrowth.

C. Inhibition of histone deacetylases with a TSA-coated bead implanted into the early limb bud results in precocious Hoxa13 expression and specifically reduced skeletal elements of the zeugopod

D. Inhibition of HAT proteins with a TSA-coated bead implanted into the early limb bud results in Hoxa13 expression and specifically reduced skeletal elements of the zeugopod

E. The epigenetic hold on gene Hoxa13 expression to allow the necessary time for zeugopod development.

F. The epigenetic hold on gene Hoxa13 expression to allow the necessary time for autopod development.

Which of the following combinations are correct?

#Unit 5. Developmental Biology
  1. A, C and F
  2. B, D and E
  3. A, C and E
  4. C and E only