TLS Online TPP Program

#Question id: 7210


Model for limb patterning by opposing gradients of retinoic acid (blue shading) and of FGFs and Wnts (pink shading). According to this graph, Which of the following statements are correct?

#Unit 5. Developmental Biology
  1. RA and Fgf8 differentially regulate proximal-distal determining genes, such as Meis1/2, Hoxa11, and Hoxa13 in the stylopod, zeugopod and autopod, respectively.
  2. RA and Fgf8 differentially regulate anterior-posterior determining genes, such as Meis1/2, Hoxa11, and Hoxa13 in the stylopod, zeugopod and autopod, respectively.
  3. RA and Fgf8 differentially regulate dorsal-ventral determining genes, such as Meis1/2, Hoxa11, and Hoxa13 in the stylopod, zeugopod and autopod, respectively.
  4. According to three dimensional coordinated system, A, B and C are correct.