TLS Online TPP Program

#Question id: 7219


Following statements are regarding to the role of the Disheveled and β-catenin proteins in specifying the cells of the sea urchin embryo.

A. During normal development, β-catenin accumulates predominantly in the micromeres and somewhat less in the veg2 tier cells.

B. In embryos treated with lithium chloride, β-catenin accumulates in the nuclei of all blastula cells and the cells of the animal pole become specified as ectoderm.

C. When β-catenin is prevented from entering the nuclei (i.e., it remains in the cytoplasm), the vegetal cell fates are not specified, and the entire embryo develops as a ciliated ectodermal ball.

D. When β-catenin is prevented from entering the nuclei (i.e., it remains in the cytoplasm), the vegetal cell fates are specified, and the entire embryo specified as endoderm and mesoderm .

Which of the following statements are true?

#Unit 5. Developmental Biology
  1. A and D
  2. A and B
  3. A and C
  4. B and D