Following statements are regarding to the drosophila.

 A. At the completion of oogenesis, the bicoid message is anchored at the anterior end of the oocyte and the nanos message is tethered to the posterior end in translationally dormant condition.

 B. The translation inhibitors Smaug and CUP. Smaug binds to the 3’UTR of both bicoid and nanos mRNA and recruits the CUP protein that prevents the association of the message with the ribosome as well as recruiting other proteins that deadenylate the message and target it for degradation.

 C. The bicoid-Exuperantia complex is transported out of the nurse cells and into the oocyte via microtubules (Kinesin ATPase).

 D. Two other maternally provided mRNAs—caudal and hunchback are critical for patterning the anterior and posterior regions of the body plan, respectively.

 Which of the following combination is correct?

#Question id: 2573

#Unit 2. Cellular Organization

Certain unicellular eukaryotes, including diatoms and some yeasts, have mechanisms of nuclear division that may resemble intermediate steps in the evolution of mitosis. Which of the following is a characteristic feature of nuclear division in these organisms?

#Question id: 2574

#Unit 2. Cellular Organization

Through a microscope, you can see a cell plate beginning to develop across the middle of a cell and nuclei forming on either side of the cell plate. This cell is most likely ________.

#Question id: 2575

#Unit 2. Cellular Organization

NMR studies of the pectin molecules indicate that, which one is not true for pectin ?

#Question id: 2576

#Unit 2. Cellular Organization

What effect will addition of AMP-PNP have on axonal transport?

#Question id: 2577

#Unit 2. Cellular Organization

Which of the following occur(s) during prophase?

a. Kinetochores capture microtubule (+) ends.

b. Chromosomes move poleward.

c. Chromosomes align on the spindle equator.

d. Centrosomes separate and the spindle begins to form.

e. Chromosome condensation begins.

#Question id: 2578

#Unit 2. Cellular Organization

Following statements are regarding to proteins which involve actin filament assembly.

A. To nucleate the assembly of branched actin, Arp2/3 needs to be activated by interacting with a nucleation promoting factor (NPF), in addition to associating with the side of a pre-existing actin filament.

B. The NPF WASp is inactive due to an intramolecular interaction that masks the WCA domain.

C. Two NPFs each bind an actin subunit at their WH2 domains, and together, they activate the Arp2/3 complex through its interaction with their connector and acidic domains.

D. The NPF WASp is activated by a coincidence detection mechanism by which intramolecular interaction in WASp is relieved, allowing the W domain to bind actin and the acidic A domain to activate the Arp2/3 complex.

Which of the following statements represents regulation of the Arp2/3 complex by NPF?