TLS Online TPP Program

#Question id: 7267


Endocrine disruptors can interfere with hormone function in many ways like, They can act as antagonists and inhibit the binding of a hormone to its receptor or block the synthesis of a hormone. which of the following example best explains the antagonistic effect of endocrine disruptors?

#Unit 5. Developmental Biology
  1. The endocrine disruptor diethylstilbestrol (DES), which binds to the estrogen receptor and mimics estradiol, a hormone that is very active in building the tissues of the female reproductive tract.

  2. DDE, a metabolic product of the insecticide DDT, can act as an anti-testosterone, binding to the androgen receptor and preventing normal testosterone from functioning properly.
  3. The herbicide atrazine, elevates the synthesis of estrogen and can convert testes into ovaries in frogs.
  4. Polychlorinated biphenyls (PCBs) disrupt the endocrine system is by interfering with the elimination and degradation of thyroid hormones.
More Questions
TLS Online TPP Program

#Question id: 7278

#Unit 5. Developmental Biology

The following demonstrates the blastocoel formation in the mammals. Which of the following statement is correct?

TLS Online TPP Program

#Question id: 7279

#Unit 5. Developmental Biology

X chromosome number alone is the primary sex determinant in normal drosophila because:

TLS Online TPP Program

#Question id: 7280

#Unit 5. Developmental Biology

In drosophila, Physical forces drive invagination of the ventral furrow. Following statements regarding to this process:

A. The cellularized blastoderm will begin to activate higher levels of myosin in the cells at the ventral midline and preferentially at their apical surface.

B. Epithelial adhesions paired with differential activation of dynein and tissue geometry create mechanical constraints that affect the orientation of actomyosin meshworks.

C. The A/P oriented arrays of myosin in the cells at the ventral midline generate tension along the anterior-posterior axis.

D. The combination of tissue geometry and tension of these anterior-to-posterior meshworks cause the tissue to fold outward at a right angle to the anterior-posterior axis, creating a long and narrow ventral furrow.

Which of the following statements are incorrect?

TLS Online TPP Program

#Question id: 7281

#Unit 5. Developmental Biology

Evolutionary conservation of homeotic gene organization and transcriptional expression in fruit flies and mice is seen in the similarity between the Hom-C cluster on Drosophila chromosome 3 and the four Hox gene clusters in the mouse genome.

 

According to this figure, Which of the following statement is correct?

TLS Online TPP Program

#Question id: 7282

#Unit 5. Developmental Biology

In humans, neural tube closure defects occur in about 1 in every 1000 live births. Failure to close the neural tube can result from both genetic and environmental causes. A recent report has demonstrated that zinc deficiency disrupts neural tube closure by:

TLS Online TPP Program

#Question id: 7283

#Unit 5. Developmental Biology

The Drosophila orthodenticle gene and the vertebrate Otx genes are homologous and provide a good example of the conservation of gene function during evolution. Which of the following statement is correct regarding to the expression of gene expression.