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TLS Online TPP Program

#Question id: 7303

The ‘quartet model’ explains how the protein products of the ABCE-function genes might interact to control floral organ identity. Following statements are based on this model. Which one of them is incorrect?

#Unit 5. Developmental Biology
  1. There are four combinations of floral MADS-box proteins. SEP proteins may form heterodimers with A (AP1) and B (AP3/ PI) proteins (for petals), B (AP3/PI) and C(AG) proteins (for stamens), and C (AG) protein (for carpels).
  2. All these genes, with the exception of AP2 (and its homologues), are MADS-box genes, a broad family of eukaryotic genes that encode transcription factors containing a highly conserved DNA-binding domain (MADS domain).
  3. The protein quartets are transcription factors and may function by binding to the promoter regions of target genes.

  4. According to the model, one dimer of each tetramer recognize two different sites on the same DNA strand, thus bringing these areas into proximity via DNA-bending.

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TLS Online TPP Program

#Question id: 3808

#Unit 3. Fundamental Processes

Fibroblast cells from several different xeroderma pigmentosa patients were cultured, then fused in intergenic complementation studies. Which cell fusions would not result in a hybrid capable of repairing damaged DNA?
TLS Online TPP Program

#Question id: 3809

#Unit 3. Fundamental Processes

MMR is a highly conserved biological pathway. Several human MMR proteins have been identified based on their homology to E. coli MMR proteins. Match the following

Human

Function

1. MSH2-MSH6

A. DNA mismatch/damage recognition

2. MLH-PMS

B. Molecular matchmaker

3. MutH

C. Strand discrimination

D. Absent in Human


TLS Online TPP Program

#Question id: 3810

#Unit 3. Fundamental Processes

In the diagram below, the dotted line marks the point of initiation of bidirectional replication

A. On the right side of the dotted line, leading strand synthesis occurs using the lower strand as the template.

B. On the right side of the dotted line, leading strand synthesis occurs using the upper strand as the template.

C. A ligase deficient (lig- ) mutant would affect replication of t11e upper strand on the left side of the dotted line.

D. A ligase deficient (lig- ) mutant would affect replication of the lower strand on the left side

of the dotted line_

Which one of the following options represents the combinations of the CORRECT statements?
TLS Online TPP Program

#Question id: 3811

#Unit 3. Fundamental Processes

The mechanism of DNA replication is studied in an E. coli replication fork. Which is a characteristic of this replication fork?
TLS Online TPP Program

#Question id: 3812

#Unit 3. Fundamental Processes

The mechanism of DNA replication is studied in an E. coli replication fork. Which is a characteristic of this replication fork?
TLS Online TPP Program

#Question id: 3813

#Unit 3. Fundamental Processes

The mechanism of DNA replication is studied in an E. coli replication fork. Which is a property of Okazaki pieces in an E. coli replication fork?