#Question id: 12143
#Unit 10. Ecological Principles
#Question id: 2977
#Unit 2. Cellular Organization
The mitotic exit network that localizes to spindle pole bodies and whose activity is regulated by spindle position belongs to the family of signaling pathways known as the Hippo pathway in metazoans. Following statements are-
A. The conserved core of the Hippo signaling pathways consists of the Hippo protein kinase, which activates the Lats-Mob1 kinase.
B. The kinases are organized by a scaffolding molecule that, at least in budding and fission yeasts, targets the kinase cascade to centrosomes.
C. As in many kinase signaling cascades, a GTPase controls the activity of the mitotic exit network and the septation initiation network.
D. In metazoans, activation of the Hippo pathway leads to tissue overgrowth because the transcriptional activator TAZ (known as YAP in the mouse) constitutively promotes the expression of growth- and proliferation-promoting genes.
Which of the following statements are incorrect?
#Question id: 2152
#Unit 2. Cellular Organization
Precursors of membrane phospholipids are
a. soluble in the cytosol.
b. incorporated into biosynthetic intermediates.
c. sometimes complexed with fatty-acid-binding proteins.
d. stored in glycerolosomes.
e. sometimes activated by conjugation with CDP.
#Question id: 2252
#Unit 2. Cellular Organization
The generation and maintenance of a membrane electric potential requires which of the following:
a. active pumping of ions
b. ion-specific membrane channel proteins
c. ATP
d. a generally permeable membrane
#Question id: 20276
#Unit 7. System Physiology – Animal