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TLS Online TPP Program

#Question id: 9178

A fish swimming into an estuary from a river would have which of the following as its greatest physiological challenge?

#Unit 9. Diversity of Life Forms
  1. The high water flow would make the fish expend more energy.
  2. The low oxygen content would give the fish difficulty in swimming aerobically.
  3. The temperature change would stress the fish by denaturing its proteins.
  4. The change in water solute content would challenge the osmotic balance of the fish.
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TLS Online TPP Program

#Question id: 13158

#Unit 2. Cellular Organization

In which process, protein are first encapsulated in a membrane, then the contents of the resulting vesicle are degraded after the vesicle docks with a cytosolic lysosome.
TLS Online TPP Program

#Question id: 13159

#Unit 4. Cell Communication and Cell Signaling

How signaling is involved in ensuring that yeast cells fuse only with cells of the opposite mating type?
TLS Online TPP Program

#Question id: 13160

#Unit 4. Cell Communication and Cell Signaling

According to the Switching mechanism, monomeric G proteins exist in two states. Match the following states (Column I) with correct mechanism (Column II).

Column I

Column II

A. “ON” state 

i. switch I and switch II, are bound to the terminal γ phosphate of GTP through interactions with the backbone amide groups of conserved threonine and glycine residues.

B. “OFF” state

ii. GTPase-activating proteins

 

iii. guanine nucleotide exchange factor

 

iv. Due to the removal of the γ phosphate by GTPase-catalyzed hydrolysis causes switch I and switch II to relax into a different conformation

TLS Online TPP Program

#Question id: 13161

#Unit 4. Cell Communication and Cell Signaling

Which of the following mechanism depends on the activation of heterotrimeric G proteins?
TLS Online TPP Program

#Question id: 13162

#Unit 4. Cell Communication and Cell Signaling

In the amoeba Dictyostelium discoideum, cAMP acts as an extracellular signalling molecule and binds to and signals via a G protein–coupled receptor; it is not a second messenger. Amoeba cells were transfected with genes encoding two fusion proteins: a Gα fused to cyan fluorescent protein (CFP), and a Gβ fused to yellow fluorescent protein (YFP). CFP normally fluoresces 490-nm light; YFP, 527-nm light. In which conditions fluorescence
energy transfer occur from CFP to YFP?
TLS Online TPP Program

#Question id: 13163

#Unit 4. Cell Communication and Cell Signaling

Following statements are regarding to the interaction between β2-adrenergic receptor and G- protein.