TLS Online TPP Program

#Question id: 718


Poly- L -leucine in an organic solvent such as dioxane is a helical, whereas poly- L isoleucine is not. Why do these amino acids with the same number and kinds of atoms have different helix-forming tendencies?

#Unit 1. Structure and Function of Biomolecules
  1. Leucine has bulky side chain than isoleucine so it forms helix.

  2. Methyl group at γ position of isoleucine cause stearic hindrance and blocks helix formation tendency

  3. Due to the stearic hindrance caused by β carbon- methyl group, isoleucine can’t form helix. Methyl group at γ position of isoleucine cause stearic hindrance and blocks helix formation tendency.

  4. Isoleucine has chiral carbon due to which it can,t form poly-L isoleucine helix.

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TLS Online TPP Program

#Question id: 4495

#Unit 3. Fundamental Processes

_ elements can block this spreading, protect genes from both indiscriminate activation and repression.

TLS Online TPP Program

#Question id: 4496

#Unit 3. Fundamental Processes

Facilitates chromatin transcription was identified in human cell extracts, this factor makes transcription on chromatin templates much more efficient, choose correct statements;

TLS Online TPP Program

#Question id: 4497

#Unit 3. Fundamental Processes

Elongation, termination of transcription, and RNA processing are interconnected, presumably to ensure their proper coordination,

   Elongation factors

I.    hSPT5

To recruit the 5’ -capping enzyme to the CTD tail of polymerase

 II.   TAT-SF1

To recruits components of the splicing machinery to polymerase with a Ser-2 phosphorylated tail

TLS Online TPP Program

#Question id: 4498

#Unit 3. Fundamental Processes

Which enzyme is used in this particular mechanism;

TLS Online TPP Program

#Question id: 4499

#Unit 3. Fundamental Processes

The final RNA processing event, polyadenylation of the 3’end of the mRNA, is intimately linked with the termination of transcription. Just as with capping and splicing, the polymerase CTD tail is involved in recruiting some of the enzymes necessary for polyadenylation,

TLS Online TPP Program

#Question id: 4500

#Unit 3. Fundamental Processes

The free end of the second RNA is uncapped and thus can be distinguished from genuine transcripts. This new RNA is recognized by an RNase called, in yeast, _ and in humans_ that is loaded onto the end of the RNA by another protein that binds the CTD of RNA polymerase.