The structure of alpha helix is stabilized by hydrogen bonds between the hydrogen atom attached to the electronegative nitrogen atom of a peptide linkage and the electronegative carbonyl oxygen atom of the fourth amino acid on the amino-terminal side of that peptide bonds. Within the helix, every peptide bond (except those close to each end of the helix) participates in such hydrogen bonding. Each successive turn of the helix is held to adjacent turns by three to four hydrogen bonds, conferring significant stability on the overall structure. Which of the following are correct statements regarding these findings?

A. At the ends of a helical segment, there are always three or four amide carbonyl or amino groups that participate in this stabilised helical pattern of hydrogen bonding.

B. Helix ends are exposed to the surrounding solvent, where they hydrogen-bond with water, or other parts of the protein may cap the helix to provide the needed hydrogen-bonding partners.

C. Helix can form in polypeptides consisting of either L- or D-amino acids but a D-amino acid will disrupt a regular structure consisting of L-amino acids, and vice versa.

D. The most stable form of a helix consisting of L-amino acids is left-handed.

E. 310 helix occupies similar place as turns in Ramachandran plot due to its confirmation

#Question id: 5708

#Unit 8. Inheritance Biology

If non-disjunction occurs in meiosis I, which of the following scenario is most likely to occur?

#Question id: 5709

#Unit 8. Inheritance Biology

What is probability of couple where male is karyotypically normal and the female in pericentric inversion in heterozygous condition produced child with disability if 50% chance of crossing over takes placed within pericentric inversion. (Note: Duplication and deletion in gamete will results  in disability)

#Question id: 5710

#Unit 8. Inheritance Biology

This cytological analysis, chromosome (A) represents the normal condition and the centromere position. Assume that only one structural chromosome aberration occurs in the other chromosomes

#Question id: 5711

#Unit 8. Inheritance Biology

Which of the following is results of Crossing over?

#Question id: 5712

#Unit 8. Inheritance Biology

In each of the following cases, determine the consequences of a single crossover within the inverted region of a pair of homologous chromosomes with the gene order A B C D in one chromosome and a c b d in the other. There is a two situation of centromere for that gene. 

(A) Centromere is not included within the inversion.

(B) Centromere is included within the inversion

Following consequence are resulting are

I - The crossover chromatids consist of a dicentric and an acentric

II- One Cross over product is duplicated for the terminal region contain in A and deficient for the terminal region containing D

III- Both cross over products is monocentric

Following is correct combination for consequence?

#Question id: 5713

#Unit 8. Inheritance Biology

Following some statement are correct?

A) Translocation may be associated with movement of genetic material within the same chromosome

B) A person that is heterozygous for translocation may result in non viability in their zygote

C)  A person that is heterozygous for inversion may result in non viability in their recombinant zygote

D) A person that is heterozygous for translocation and lack of crossing over within translocated area result in all viable gametes