TLS Online TPP Program

#Question id: 10285


Some of the statements given shows the activity of PFK-1 and PFK-2, which of the following statements incorrectly shown these enzyme activity?

#Unit 6. System Physiology – Plant
  1. Fructose 2,6-bisphosphate is formed by phosphorylation of fructose 6-phosphate, catalyzed by phosphofructokinase-2 (PFK-2), and is broken down by fructose 2,6-bisphosphatase (FBPase-2)
  2. fructose 2,6-bisphosphate is an allosteric activator of PFK-1 activity
  3. PFK-1 is virtually inactive in the absence of fructose2,6-bisphosphate, fructose 2,6-bisphosphate has the opposite effect on FBPase-1: it reduces its affinity for its substrate, thereby slowing gluconeogenesis
  4. cAMP-dependent protein kinase, which transfers a phosphoryl group from ATP to the bifunctional protein PFK-1/FBPase-1. Phosphorylation of this protein enhances its FBPase-1 activity and inhibits its PFK-1 activity