Oxidative decarboxylation of pyruvate to acetyl-CoA by the PDH complex, how the pyruvate dehydrogenase complex carries out the five consecutive reactions in the decarboxylation and dehydrogenation of pyruvate?

 A) Pyruvate reacts with the bound thiamine pyrophosphate (TPP) of pyruvate dehydrogenase, undergoing decarboxylation to the hydroxyethyl derivative

 B) A transesterification in which the —SH group of CoA replaces the —SH group of E2 to yield acetyl-CoA and the fully reduced (dithiol) form of the lipoyl group

 C) The reduced FADH2 of E3 transfers a hydride ion to NAD1 , forming NADH, the enzyme complex is now ready for another catalytic cycle

 D) The transfer of two electrons and the acetyl group from TPP to the oxidized form of the lipoyllysyl group of the core enzyme, dihydrolipoyl transacetylase, to form the acetyl thioester of the reduced lipoyl group

 E) Dihydrolipoyl dehydrogenase promotes transfer of two hydrogen atoms from the reduced lipoyl groups of E2 to the FAD prosthetic group of E3 , restoring the oxidized form of the lipoyllysyl group of E2

 Find out the correct sequence of action of this complex enzyme?

#Question id: 4899

#Unit 8. Inheritance Biology

In Neurospora a cross between the genotypes 'A' and 'a' results in an ascus with ascospores of genotypes as shown below: 

 Statements A to D are events that could have occurred during meiosis.

A) Class I is results of no crossing over between the centromere and gene.

B) Class II is results of single crossing over between the centromere and gene

C) Class I shows segregation of alleles 'A' and 'a' in meiosis II

D) Class II shows segregation of alleles 'A' and 'a' in meiosis II

#Question id: 4900

#Unit 8. Inheritance Biology

The chlorophyll-deficient types occur in a particular plant species due to a mutation in the DNA of the chloroplast itself, Female cytoplasm chlorophyll-deficient organisms crossed with male normal chlorophyll will produce progeny

#Question id: 4900

#Unit 8. Inheritance Biology

The chlorophyll-deficient types occur in a particular plant species due to a mutation in the DNA of the chloroplast itself, Female cytoplasm chlorophyll-deficient organisms crossed with male normal chlorophyll will produce progeny

#Question id: 4901

#Unit 8. Inheritance Biology

Assume that the alleles A (dominant) and a (recessive) show a maternal effect mode of inheritance. In a cross between an Aa female and an aa male, what would be the phenotypes of the progeny?

#Question id: 4902

#Unit 8. Inheritance Biology

Leber hereditary optic neuropathy (LHON) is mitochondrial diseases present in family. Which of the following observation is correct?

#Question id: 4903

#Unit 8. Inheritance Biology

 In genetic maternal effect