Oxidative decarboxylation of pyruvate to acetyl-CoA by the PDH complex, how the pyruvate dehydrogenase complex carries out the five consecutive reactions in the decarboxylation and dehydrogenation of pyruvate?

 A) Pyruvate reacts with the bound thiamine pyrophosphate (TPP) of pyruvate dehydrogenase, undergoing decarboxylation to the hydroxyethyl derivative

 B) A transesterification in which the —SH group of CoA replaces the —SH group of E2 to yield acetyl-CoA and the fully reduced (dithiol) form of the lipoyl group

 C) The reduced FADH2 of E3 transfers a hydride ion to NAD1 , forming NADH, the enzyme complex is now ready for another catalytic cycle

 D) The transfer of two electrons and the acetyl group from TPP to the oxidized form of the lipoyllysyl group of the core enzyme, dihydrolipoyl transacetylase, to form the acetyl thioester of the reduced lipoyl group

 E) Dihydrolipoyl dehydrogenase promotes transfer of two hydrogen atoms from the reduced lipoyl groups of E2 to the FAD prosthetic group of E3 , restoring the oxidized form of the lipoyllysyl group of E2

 Find out the correct sequence of action of this complex enzyme?

#Question id: 3604

#Unit 8. Inheritance Biology

Genes A, B and C. control three phenotypes which assort independently; A plant with the genotype aaBbCc were cross with AabbCc. What is the probability for progeny which show the dominant phenotype for AT LEAST ONE of the phenotypes controlled by genes A, B and C?

#Question id: 3605

#Unit 8. Inheritance Biology

Male Plant blue flower with long pollen was crossed with female plant white flower with long pollen. Analysis of progeny of this cross showed that 50% of the progeny was red with long pollen while the remaining 50% of the progeny was white with long pollen. Which one of the following statements is a possible explanation of the above results?

#Question id: 3606

#Unit 8. Inheritance Biology

Genes A, B and C. control three phenotypes which assort independently; A plant with the genotype Aa Bb Cc is selfed. What is the probability for progeny which show the heterozygocity for AT LEAST ONE locus?

#Question id: 3607

#Unit 8. Inheritance Biology

Cystic fibrosis is caused by a recessive lethal gene and can be detected by an excess concentration of chloride in sweat. If a sweat test reveals a man to be heterozygous and his wife to be homozygous normal, what are the chances that their children will have the disease?

#Question id: 3608

#Unit 8. Inheritance Biology

Mendel crossed plants with the seed characters round and yellow with plants having the contrasting seed characters wrinkled and green. Round is dominant

to wrinkled, and yellow is dominant to green. The F1 progeny were all round and yellow. What will be genotype ratio in F2 generation?

#Question id: 3609

#Unit 8. Inheritance Biology

In humans, the dominance relationship between the A and B alleles of the ABO blood group gene is an example of