26-residue peptide composed of alanine and leucine shows a circular dichroism (CD) spectrum characteristic of α-helix at 50°C in 5 mM phosphate buffer at pH 7.4. When the peptide solution is cooled gradually to 25°C, and the CD spectra are recorded at different temperatures, the most likely observation will be that

TLS Online TPP Program

#Question id: 12212

#Unit 7. System Physiology – Animal

 A 71-year-old man with upper abdominal pain and blood in the stool takes NSAIDS for the pain and washes it down with whiskey. Pentagastrin administration produced lower than predicted levels of gastric acid secretion. Secretion of which of the following substances is most likely to be diminished in this patient with gastritis?

TLS Online TPP Program

#Question id: 12213

#Unit 7. System Physiology – Animal

The gastric phase of gastric secretion accounts for about 60% of the acid response to a meal. Which of the following can virtually eliminate the secretion of acid during the gastric phase?

TLS Online TPP Program

#Question id: 12214

#Unit 7. System Physiology – Animal

A 53-year-old man with a recurrent history of ulcer disease associated with diarrhea and a strong family history of duodenal ulcer disease is suspected of having Zollinger-Ellison syndrome (gastrinoma). Secretin (2 units/kg) was given as a rapid intravenous injection to test for gastrinoma. Which of the following results would support the existence of gastrinoma following secretin administration?

TLS Online TPP Program

#Question id: 12215

#Unit 7. System Physiology – Animal

Damage to the gastric mucosal barrier is a forerunner of gastric ulcer. Which of the following can both damage the gastric mucosal barrier and stimulate gastric acid secretion?

TLS Online TPP Program

#Question id: 12216

#Unit 7. System Physiology – Animal

Gastric emptying is regulated to ensure the chyme enters the duodenum at an appropriate rate. Which of the following factors promotes gastric emptying?

TLS Online TPP Program

#Question id: 12217

#Unit 7. System Physiology – Animal

Cystic fibrosis is the most common cause of pancreatitis in children. Which of the following best explains the mechanism of cystic fibrosis–induced pancreatitis?