TLS Online TPP Program

#Question id: 10461


Model of cry1 interactions with COP1/SPA1 in the regulation of photomorphogenesis, what will happen in the dark as well as in the light in wild type condition of cryptochrome?

a) In the dark, COP1/SPA1 acts to degrade transcription factors such as HY5, which is required for photomorphogenesis

b) In the dark, cry1 is activated by phosphorylation and forms a complex with COP1 and SPA1 via the C-terminal domain, preventing them from degrading protein HY5

c) In the light, COP1/SPA1 acts to degrade transcription factors such as HY5, which is required for photomorphogenesis

d) In the light, cry1 is activated directly by blue light and indirectly by blue light induced phosphorylation and forms a complex with COP1 and SPA1 via the C-terminal domain, preventing them from degrading protein HY5

e) In light as well as in dark both case cryptochrome perfom same function such as forming a complex with COP1/ SPA1 thereby promoting an increase in HY5 protein levels and transcription

Which of the following combinations from the above statements of cryptochrome is incorrect?

#Unit 6. System Physiology – Plant
  1. B, C and E     
  2. A, D and E
  3. A and D      
  4. C and E
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TLS Online TPP Program

#Question id: 33475

#Unit 2. Cellular Organization

With pulsed-field gel electrophoresis, which can separate DNA molecules up to 107 bp in length. The results of pulsed-field gel electrophoresis of the DNA from the yeast Saccharomyces cerevisiae are shown in Figure. How many chromosomes does S. cerevisiae have?


TLS Online TPP Program

#Question id: 33476

#Unit 2. Cellular Organization

Find true and false statements
A. The structures of eukaryotic genes show extensive variation. 
B. Some eukaryotic genes are uninterrupted and their sequences are colinear with those of the corresponding mRNAs. 
C. Most multicellular eukaryotic genes are interrupted, but the introns vary enormously in both number and size.

TLS Online TPP Program

#Question id: 33477

#Unit 2. Cellular Organization

Finding: Ancestry have similar organizations with conservation of the positions (of at least some) of the introns.

Example: The globin and DHFR genes are examples of a genes that share a common ancestor

TLS Online TPP Program

#Question id: 33478

#Unit 2. Cellular Organization

Find true and false statements
A. Comparisons of related genes in different species show that the sequences of the corresponding exons are usually conserved
B. when two genes are related, the relationship between their exons is closer than the relationship between their introns.
C. The sequences of the introns are much less similar.
D. Introns evolve much more rapidly than exons because of the lack of selective pressure to produce a polypeptide with a useful sequence.

TLS Online TPP Program

#Question id: 33479

#Unit 2. Cellular Organization


TLS Online TPP Program

#Question id: 33480

#Unit 2. Cellular Organization

Finding: The overall degree of divergence between two homologous exons in related genes corresponds to the differences between the polypeptides.

Reason: Overall degree of divergence between two homologous exons is mostly a result of base substitutions.