TLS Online TPP Program

#Question id: 10463


LOV1 and LOV2, each binding a chromophore flavin mononucleotide (FMN), which one of the following statements shows incorrect prediction about LOV domains?

#Unit 6. System Physiology – Plant
  1. Upon blue-light illumination, the FMN molecule becomes covalently bound to a cysteine residue in the phototropin molecule, forming a cysteine-flavin covalent adduct
  2. Phototropin contains two light-sensing LOV domains, the LOV1 domain is primarily responsible for kinase activation in response to blue light
  3. The three-dimensional structure of the LOV2 domain resembles a closed molecular hand holding the FMN tightly by noncovalent interactions inside its core
  4. In the dark, one FMN molecule is noncovalently bound to each LOV domain