TLS Online TPP Program

#Question id: 766


With respect to microRNAs, which, if any, of the following statements, is true?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. MicroRNA is a generic term that covers all tiny RNAs, ones that are less than 35 nucleotides long when mature.

  2. MicroRNA genes often occur in gene clusters within introns of protein-coding genes and are usually transcribed by RNA polymerase II.

  3. MicroRNAs regulate target genes by binding to complementary sequences on one DNA strand of the target gene.

  4. MicroRNAs normally regulate the expression of just a single target gene.

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TLS Online TPP Program

#Question id: 177

#Unit 1. Molecules and their Interaction Relevant to Biology

The titration curve of alanine shows the ionization of two functional groups with pKa values of 2.34 and 9.69, corresponding to the ionization of the carboxyl and the protonated amino groups, respectively. The titration of di-, tri-, and larger oligopeptides of alanine also shows the ionization of only two functional groups, although the experimental pKa values are different. The trend in pKa values is summarized in the table. Which of the following is a reason for this shift in pK values

TLS Online TPP Program

#Question id: 178

#Unit 1. Molecules and their Interaction Relevant to Biology

Given the pKa values of different acidic sites in cysteine, the principal ionic form which will never exist at any pH

TLS Online TPP Program

#Question id: 179

#Unit 1. Molecules and their Interaction Relevant to Biology

The average molecular weight of the 20 standard amino acids is 138, but biochemists use 110 when estimating the number of amino acids in a protein of known molecular weight.  Why?

TLS Online TPP Program

#Question id: 180

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following statements about aromatic amino acids is correct?

TLS Online TPP Program

#Question id: 181

#Unit 1. Molecules and their Interaction Relevant to Biology

Titration of valine by a strong base, for example NaOH, reveals two pK’s. The titration reaction occurring at pK2 (pK2 = 9.62) is:

TLS Online TPP Program

#Question id: 182

#Unit 1. Molecules and their Interaction Relevant to Biology

Which amino acid is least likely to participate in acid-base catalysis?