Match the structural properties of DNA with the respective types of DNA in which they are found.

COLUMN – I	COLUMN – II
A. Pitch per turn of helix	1. 45.6 angstrom 2. 24.6 angstrom 3. 33.2 angstrom
B. Helix packing diameter	1. 23.7 angstrom 2. 18.4 angstrom 3. 25.5 angstrom
C. Major-groove proportions	1. Flattened out on helix surface 2. Extremely narrow but very deep 3. Wide and of intermediate depth
D. Minor-groove proportions	1. Very broad but shallow 2. Extremely narrow but very deep 3. Narrow and of intermediate depth

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#Question id: 861

#Unit 1. Molecules and their Interaction Relevant to Biology

Alexander Varshavsky discovered, the half-lives of many cytoplasmic proteins vary with the identities of their N-terminal residues via the so-called N-end rule:-

A. Destabilizing N-terminal residues Asp, Arg, Leu, Lys, and Phe have half-lives of	i. Only 2 to 3 minutes,
B. Stabilizing N-terminal residues Ala, Gly, Met, Ser, Thr, and Val have half-lives of	ii. >10 hours in prokaryotes iii. >20 hours in eukaryotes.

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#Question id: 862

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the following

lysosomal protein degradation pathways	Found in
1. Nonselective	a-well-nourished cells	i-containing the pentapeptide Lys-Phe-Glu-Arg-Gln
2- Selective	b-starving cells

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#Question id: 863

#Unit 1. Molecules and their Interaction Relevant to Biology

Ubiquitinated proteins are proteolytically degraded in an ATP-dependent process mediated by a large (∼2500 kD, 26S) multiprotein complex named the 26S proteasome;

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#Question id: 864

#Unit 1. Molecules and their Interaction Relevant to Biology

Which one is not the appropriate function of Heat Shock Proteins;

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#Question id: 865

#Unit 1. Molecules and their Interaction Relevant to Biology

In autophagy, the endoplasmic reticulum (ER) first gives rise to a cup-shaped, membranous cisterna called the______

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#Question id: 866

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is known as Sanger’s reagent